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产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 100 |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
form【形式】 | liquid |
species reactivity | human, rat, mouse |
concentration【浓度】 | 0.74 mg/mL |
technique(s) | immunohistochemistry: 1:50-1:200 western blot: 1:1000-1:3000 |
UniProt accession no.【UniProt登记号】 | O43490 |
shipped in【运输】 | wet ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... PROM1(8842) |
基本信息
General description【一般描述】 | This gene encodes a pentaspan transmembrane glycoprotein. The protein localizes to membrane protrusions and is often expressed on adult stem cells, where it is thought to function in maintaining stem cell properties by suppressing differentiation. Mutations in this gene have been shown to result in retinitis pigmentosa and Stargardt disease. Expression of this gene is also associated with several types of cancer. This gene is expressed from at least five alternative promoters that are expressed in a tissue-dependent manner. Multiple transcript variants encoding different isoforms have been found for this gene. |
Immunogen【免疫原】 | A synthetic peptide corresponding to a sequence within amino acids 750-850 of human CD133 (NP_006008.1). |
Physical form【外形】 | Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |