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Anti- APP antibody produced in rabbit

产品编号:4104176
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
41041764660
产品性质
biological source【生物来源】
rabbit
Quality Level【质量水平】
100
antibody product type
primary antibodies
clone【克隆】
monoclonal
form【形式】
liquid
species reactivity
mouse, rat, human
concentration【浓度】
0.93 mg/mL
technique(s)
western blot: 1:500-1:2000
UniProt accession no.【UniProt登记号】
P05067
shipped in【运输】
wet ice
storage temp.【储存温度】
−20℃
Gene Information
human ... APP(351)
基本信息
General description【一般描述】
This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. In addition, two of the peptides are antimicrobial peptides, having been shown to have bacteriocidal and antifungal activities. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Aug 2014]
Immunogen【免疫原】
A synthesized peptide derived from human APP
Physical form【外形】
Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
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