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Angiostatin K1-3 human
| 产品编号： | 4104146 |
| 规格： | recombinant, expressed in E. coli, ≥95% (SDS-PAGE) |
| CAS NO： | 2231800-24-9 |
| 包装规格： | 100 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
2231800-24-9
Angiostatin K1-3 human
Angiostatin Kringles 1-3
产品性质
| biological source【生物来源】 | human |
| recombinant【重组】 | expressed in E. coli |
| Assay【测定】 | ≥95% (SDS-PAGE) |
| form【形式】 | lyophilized |
| mol wt【分子量】 | 30.0 kDa |
| packaging【包装】 | pkg of 100 μg |
| impurities【杂质】 | Endotoxin, tested |
| NCBI accession no.【NCBI登记号】 | P00747 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... PLG(5340) |
基本信息
| General description【一般描述】 | Ang K1-3 is a single, non-glycosylated polypeptide chain containing 259 amino acids. It represents a proteolytic fragment of plasminogen containing the first three kringle structures. A specific inhibitor of endothelial cell growth and angiogenesis. Displays increased inhibitory activity (ED50 =70 nM) relative to kringles 1-4 (ED50 = 135 nM). Ang K1-3 reduces endothelial cell proliferation and acts as a potent inhibitor of angiogenesis and tumor growth. |
| Physical form【外形】 | From 20 mM sodium acetate, pH 5.5, 4% mannitol |
| Reconstitution【重悬】 | Centrifuge the vial prior to opening. Reconstitute in sterile distilled H?O or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml. |
安全信息
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
