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AITRL human

产品编号:4103920
规格:recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture
包装规格:20 μG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
410392020 μG4820
产品别名

AITRL human

TNFSF18

Activation-induced TNFR member Ligand

基本信息
NACRES
NA.32
General description【一般描述】
AITRL, a member of the TNF superfamily, is expressed in endothelial cells, and signals through the AITR receptor. AITRL regulates T-cell proliferation and survival, and effectuates the interaction between T lymphocytes and endothelial cells. The AITRL gene codes for a type II transmembrane protein comprised of 177 amino acids, including a 28 amino acid cytoplasmic region, a 21 amino acid transmembrane domain and a 128 amino acid extracellular domain. Recombinant human soluble AITRL is a 14.3 kDa protein, containing 126 amino acid residues corresponding to the extracellular domain of AITRL.
Biochem/physiol Actions【生化/生理作用】
AITRL, a member of the TNF superfamily, is expressed in endothelial cells, and signals through the AITR receptor. Recombinant human soluble AITRL is a 14.3 kDa protein, containing 126 amino acid residues corresponding to the extracellular domain of AITRL.
Sequence【序列】
ETAKEPCMAK FGPLPSKWQM ASSEPPCVNK VSDWKLEILQ NGLYLIYGQV APNANYNDVA PFEVRLYKNK DMIQTLTNKS KIQNVGGTYE LHVGDTIDLI FNSEHQVLKN NTYWGIILLA NPQFIS
Physical form【外形】
Lyophilized from 10 mM Tris, pH 8.0.
Reconstitution【重悬】
Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8℃ for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20℃ to -80℃.
产品性质
biological source【生物来源】
human
recombinant【重组】
expressed in E. coli
Assay【测定】
≥98% (HPLC)
≥98% (SDS-PAGE)
form【形式】
lyophilized
mol wt【分子量】
14.3 kDa
packaging【包装】
pkg of 20 μg
technique(s)
cell culture | mammalian: suitable
impurities【杂质】
<0.1 EU/μg endotoxin, tested
color【颜色】
white to off-white
UniProt accession no.【UniProt登记号】
Q9UNG2
shipped in【运输】
wet ice
storage temp.【储存温度】
−20℃
Gene Information
human ... TNFSF18(8995)
安全信息
Pictograms【象形图】
GHS07
Signal word【警示用语:】
Warning
Hazard Statements
H315 - H319 - H335
Precautionary Statements
P261 - P305 + P351 + P338
Hazard Classifications【危险分类】
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Storage Class Code【储存分类代码】
13 - Non Combustible Solids
WGK
WGK 3
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