Anti-Cytokeratin 18 Antibody, clone RCK106

32160702

NA.41

Cytokeratins are a subfamily of intermediate filament proteins and are characterized by a remarkable biochemical diversity, represented in epithelial tissues by at least 20 different polypeptides. They range in molecular weight from between 40 kDa and 68 kDa and isoelectric pH between 4.9 - 7.8, The individual cytokeratin polypeptides are designated 1-20. The various epithelia in the human body usually express cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of maturation or differentiation within an epithelium. Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies.

Cytokeratin 18. MAB3236 reacts exclusively with human glandular epithelial cells of the digestive, respiratory, and urogenital tracts, endocrine and exocrine cells and mesothelial cells as well as adenocarcinomas originating from them.

SPECIES REACTIVITY:

Human only. Does not react with other species.

Cytoskeletal preparation of human bladder carcinoma cell line T24.

Research Category
Cell Structure
Anti-Cytokeratin 18 Antibody, clone RCK106 detects level of Cytokeratin 18 & has been published & validated for use in FC, WB, IC, IH(P).
Research Sub Category
Cytokeratins
Western blot

Immunohistochemistry on frozen and paraffin embedded tissue sections.

Immunocytochemistry

Flow cytometry

Optimal working dilutions must be determined by the end user.

Replaces: 04-586

Format: Purified
Liquid in buffer with 0.1% sodium azide.

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

100

mouse

purified antibody

primary antibodies

RCK106, monoclonal

human

Chemicon^®

flow cytometry: suitable
immunocytochemistry: suitable
immunohistochemistry: suitable (paraffin)
western blot: suitable

IgG1

NM_000224.2
NM_199187.1

P05783

dry ice

human ... KRT18(3875)

Maintain at -20°C in undiluted aliquots up to 6 months. Avoid repeated freeze/thaw cycles.

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

12 - Non Combustible Liquids

WGK 2