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UbcH7 Conjugating Enzyme, 100 μg
产品编号: | 4101819 |
规格: | UbcH7 is a class I enzyme which functions in the stress response & the control of transcription factors. The enzyme is ubiquitously expressed with high levels of expression seen in adult muscle. |
包装规格: | 100 μG |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
基本信息
eCl@ss | 32160405 |
NACRES | NA.32 |
General description【一般描述】 | UbcH7 is a class I enzyme which functions in the stress response and the control of transcription factors. The enzyme is ubiquitously expressed with high levels of expression seen in adult muscle. It has been demonstrated to participate in the ubiquitinylation of p53, c-Fos and NF-κB. UbcH7 is one of two E2s (UbcH5 being the other) with which HECT domain proteins interact with UbcH7 being able to efficiently substitute for UbcH5 in E6-AP-dependent ubiquitinylation. Typical enzyme concentration to support conjugation in vitro is 100nM to 1μM depending upon conditions. Product Source: Recombinant human UbcH7 Conjugating Enzyme expressed in E. coli. |
Physical form【外形】 | Purified using Ni2+ chelation chromatography with Ni2+ in limiting concentration. |
Legal Information【法律信息】 | UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany |
产品性质
Quality Level【质量水平】 | 100 |
biological source【生物来源】 | human |
Assay【测定】 | >95% (SDS-PAGE) |
mol wt【分子量】 | Mw 18 kDa |
manufacturer/tradename | Upstate® |
NCBI accession no.【NCBI登记号】 | NM_003343.4 NM_182688.1 |
UniProt accession no.【UniProt登记号】 | P60604 |
shipped in【运输】 | dry ice |
Gene Information | human ... UBE2G2(7327) |
产品说明
Storage and Stability【储存及稳定性】 | Stable for 1 year at -80°C from date of shipment. Avoid multiple freeze/thaw cycles. After initial defrost, aliquot into individual tubes and refreeze at -80°C. |
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | WGK 2 |