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基本信息
NACRES | NA.81 |
General description【一般描述】 | Epidermal melanocytes are pigment-producing cells located at the basal level of epidermis, where they interact with keratinocytes via cellular processes called dendrites. Melanin, the pigment produced by melanocytes and responsible for skin color, is then transferred to keratinocytes, where it is stored in vesicles called melanosomes located around the nucleus to provide protection from UV radiation. HEM maintain their characteristic shape in culture for many generations. They produce melanin and serve as a useful cell model for the studies of melanocyte proliferation and differentiation, as well as progression of melanocytic neoplasia. |
Cell Line Origin【细胞系来源】 | Skin |
Application【应用】 | melanin production, melanocyte proliferation, differentiation |
Components【组分】 | Basal Medium containing 30% FBS & 10% DMSO |
Preparation Note【制备说明】 |
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Subculture Routine【传代培养常规】 | Please refer to the HEM Culture Protocol. |
产品性质
biological source【生物来源】 | human skin (normal abdominal) |
Quality Level【质量水平】 | 100 |
packaging【包装】 | pkg of 500,000 cells |
growth mode【生长模式】 | Adherent |
karyotype【核型】 | 2n = 46 |
morphology【形态学】 | Epidermal |
technique(s) | cell culture | mammalian: suitable |
relevant disease(s)【相关疾病】 | metabolic disorders |
shipped in【运输】 | dry ice |
storage temp.【储存温度】 | −196℃ |
安全信息
Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
WGK | WGK 3 |