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Anti-Integrin α3 Antibody, clone ASC-1 (Azide Free)
产品别名
Anti-Integrin α3 Antibody, clone ASC-1 (Azide Free)
CD49c
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
Specificity【特异性】 | Human alpha3 integrin (CD49c) |
Immunogen【免疫原】 | Human squamous cell carcinoma cells (SCC9) |
Application【应用】 | Research Category Cell Structure Research Sub Category Integrins Inhibition (Functional Activity): A previous lot of this antibody was shown to inhibit cell attachment by inhibiting SCC9 cell adhesion to human and EHS laminin, and laminin GD-2 peptide and potentiates the inhibition of SKOV-3 cell adhesion to EHS laminin by anti-integrin alpha 5 antibody GoH3. This antibody does not inhibit cell adhesion to fibronectin or collagen type IV. Immunohistochemistry Analysis: A previous lot of this antibody was used on acetone-fixed frozen human epithelial tissues including tongue, foreskin and ovary. Not for use on formalin-fixed tissue. Flow Cytometry Analysis: A previous lot of this antibody stains human squamous cell carcinoma (SCC9), ovarian carcinoma (SKOV-3) and umbilical vein endothelial cells (HUVEC). Immunoprecipitation Analysis: A previous lot of this antibody precipitates PAGE bands of 130 kDa (reduced) or 116 kDa and 135 kDa (non-reduced) from surface-biotinylated SCC9 or SKOV-3 cells. Anti-Integrin α3 Antibody, clone ASC-1 (Azide Free) inhibits cell attachment & detects level of Integrin α3 & has been published & validated for use in FC, IP, IH, Inhibition Assays. |
Physical form【外形】 | Purified cultured supernatant in 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl, without preservatives. Format: Purified |
Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
Legal Information【法律信息】 | CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany |
产品性质
Quality Level【质量水平】 | 100 |
biological source【生物来源】 | mouse |
antibody form【抗体形式】 | culture supernatant |
antibody product type | primary antibodies |
clone【克隆】 | ASC-1, monoclonal |
species reactivity | human |
manufacturer/tradename | Chemicon® |
technique(s) | flow cytometry: suitable immunohistochemistry: suitable immunoprecipitation (IP): suitable |
isotype【同位素/亚型】 | IgG1κ |
NCBI accession no.【NCBI登记号】 | NM_002204.1 NM_005501.1 |
UniProt accession no.【UniProt登记号】 | P26006 |
shipped in【运输】 | wet ice |
Gene Information | human ... ITGA3(3675) |
产品说明
Target description【目标描述】 | 116 kDa |
Storage and Stability【储存及稳定性】 | Store at -20°C in undiluted aliquots. Avoid repeated freeze-thaw cycles. |
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | WGK 1 |