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Sorafenib tosilate
| 产品编号： | 4100324 |
| 规格： | CRS, European Pharmacopoeia (EP) Reference Standard |
| CAS NO： | 475207-59-1 |
| 包装规格： |
| 产品类别： | 进口试剂 |
| 优惠价： | 立即咨询 |
产品价格查看更多规格...
| 产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 4100324 | 1850 |
产品别名
475207-59-1
Sorafenib tosilate
N-[4-Chloro-3-(trifluoromethyl)phenyl]-N′-[4-[2-(N-methylcarbamoyl)-4-pyridyloxy]phenyl]urea, 4-methylbenzenesulfonate
BAY43-9006 tosylate salt
BAY 43-9006 tosylate salt
Sorafenib tosylate
4-[4-[[[[4-Chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]phenoxy]-N-methyl-2-pyridinecarboxamide, 4-methylbenzenesulfonate
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C21H16ClF3N4O3·C7H8SO3 |
| Molecular weight | 637.03 |
| MDL number | MFCD08235032 |
| General description【一般描述】 | This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia. |
| Biochem/physiol Actions【生化/生理作用】 | Tosylate salt of the orally active kinase inhibitor Sorafenib (BAY 43-9006) that exerts broad-spectrum anticancer efficacy in vitro and in vivo via targeting b-Raf, c-Raf (Raf-1), as well as several receptor tyrosine kinases involved in neovascularization and tumor progression, including vascular endothelial growth factor receptors 2/3 (VEGFR-2/Flk-1/KDR, VEGFR-3), platelet-derived growth factor receptor-beta (PDGFR-β), Flt-3, c-KIT, FGFR-1 (Flt-2) and RET. |
| Other Notes【其他说明】 | Sales restrictions may apply. |
产品性质
| storage temp.【储存温度】 | 2-8℃ |
| InChI | 1S/C21H16ClF3N4O3.C7H8O3S/c1-26-19(30)18-11-15(8-9-27-18)32-14-5-2-12(3-6-14)28-20(31)29-13-4-7-17(22)16(10-13)21(23,24)25;1-6-2-4-7(5-3-6)11(8,9)10/h2-11H,1H3,(H,26,30)(H2,28,29,31);2-5H,1H3,(H,8,9,10) |
| InChI key | IVDHYUQIDRJSTI-UHFFFAOYSA-N |
| packaging【包装】 | Unit quantity: 120 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue. |
安全信息
| Pictograms【象形图】 | GHS08,GHS09 |
| Signal word【警示用语：】 | Danger |
| Hazard Statements | H360FD - H362 - H372 - H410 |
| Precautionary Statements | P201 - P202 - P260 - P263 - P273 - P308 + P313 |
| Hazard Classifications【危险分类】 | Aquatic Acute 1 - Aquatic Chronic 1 - Lact. - Repr. 1B - STOT RE 1 |
| Storage Class Code【储存分类代码】 | 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects |
| WGK | WGK 3 |
