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Sorafenib for peak identification

产品编号:4100322
规格:European Pharmacopoeia (EP) Reference Standard
CAS NO:475207-59-1
包装规格:
产品类别:进口试剂
优惠价:立即咨询
产品编号包装单位单价(元)国内现货国外库存询价单
4100322 1850
产品别名

475207-59-1

Sorafenib for peak identification

N-[4-Chloro-3-(trifluoromethyl)phenyl]-N′-[4-[2-(N-methylcarbamoyl)-4-pyridyloxy]phenyl]urea, 4-methylbenzenesulfonate

BAY43-9006 tosylate salt

BAY 43-9006 tosylate salt

Sorafenib tosylate

4-[4-[[[[4-Chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]phenoxy]-N-methyl-2-pyridinecarboxamide, 4-methylbenzenesulfonate

结构式
基本信息
Empirical Formula【经验(实验)分子式】
C21H16ClF3N4O3·C7H8SO3
Molecular weight
637.03
MDL number
MFCD08235032
General description【一般描述】
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
Biochem/physiol Actions【生化/生理作用】
Tosylate salt of the orally active kinase inhibitor Sorafenib (BAY 43-9006) that exerts broad-spectrum anticancer efficacy in vitro and in vivo via targeting b-Raf, c-Raf (Raf-1), as well as several receptor tyrosine kinases involved in neovascularization and tumor progression, including vascular endothelial growth factor receptors 2/3 (VEGFR-2/Flk-1/KDR, VEGFR-3), platelet-derived growth factor receptor-beta (PDGFR-β), Flt-3, c-KIT, FGFR-1 (Flt-2) and RET.
Other Notes【其他说明】
Sales restrictions may apply.
产品性质
storage temp.【储存温度】
2-8℃
InChI
1S/C21H16ClF3N4O3.C7H8O3S/c1-26-19(30)18-11-15(8-9-27-18)32-14-5-2-12(3-6-14)28-20(31)29-13-4-7-17(22)16(10-13)21(23,24)25;1-6-2-4-7(5-3-6)11(8,9)10/h2-11H,1H3,(H,26,30)(H2,28,29,31);2-5H,1H3,(H,8,9,10)
InChI key
IVDHYUQIDRJSTI-UHFFFAOYSA-N
packaging【包装】
Unit quantity: 15 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
安全信息
Pictograms【象形图】
GHS08,GHS09
Signal word【警示用语:】
Danger
Hazard Statements
H360FD - H362 - H372 - H410
Precautionary Statements
P201 - P202 - P260 - P263 - P273 - P308 + P313
Hazard Classifications【危险分类】
Aquatic Acute 1 - Aquatic Chronic 1 - Lact. - Repr. 1B - STOT RE 1
Storage Class Code【储存分类代码】
6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
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