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Anti-SRF [Serum Response Factor] Antibody, clone 1E1
产品别名
Anti-SRF [Serum Response Factor] Antibody, clone 1E1
serum response factor (c-fos serum response element-binding transcription factor)
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | Serum response factor (SRF) is a nuclear transcription factor that binds to the serum response element (SRE), and is essential for embryonic development of the mesoderm, as well as for the maintenance of adult muscle cells and neurons. As this protein is involved in the downstream regulation of many immediate-early genes, it participates in a variety of cell functions, including cell cycle, apoptosis, cell growth, and cell differentiation. SRF is most commonly activated by serum, LPA, LPS, TPA, growth factors, including TNFalpha, as well as antioxidants and UV light. |
| Specificity【特异性】 | A weak interaction with mouse has also been observed. Reactivity with other species has not been tested. This monoclonal antibody recognizes SRF. |
| Immunogen【免疫原】 | Synthetic human SRF peptide, a.a. 406-508. |
| Application【应用】 | Detect SRF [Serum Response Factor] using this Anti-SRF [Serum Response Factor] Antibody, clone 1E1 validated for use in WB & IC. Research Sub Category Mesenchymal Stem Cells Neural Stem Cells Research Category Stem Cell Research Immunocytochemistry: Recommended working dilution is 1:500. |
| Quality【质量】 | (Based upon representative data from a previous lot). Western Blotting: Recommended working dilution is 0.5 µg/mL. |
| Physical form【外形】 | Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl, and 0.05% sodium azide. Format: Purified Protein G Purified |
| Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
产品性质
| biological source【生物来源】 | mouse |
| antibody form【抗体形式】 | purified antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | 1E1, monoclonal |
| species reactivity | mouse, human |
| technique(s) | immunocytochemistry: suitable western blot: suitable |
| input | sample type mesenchymal stem cell(s) sample type neural stem cell(s) |
| isotype【同位素/亚型】 | IgG1κ |
| UniProt accession no.【UniProt登记号】 | P11831 |
| shipped in【运输】 | wet ice |
| Gene Information | human ... ELK3(2004) |
产品说明
| Target description【目标描述】 | ~52 kDa |
| Storage and Stability【储存及稳定性】 | Maintain refrigerated at 2-8°C in undiluted aliquots for up to 12 months. Avoid repeat freeze/thaw cycles. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
