BIOshell^TM lgG, C4 2.7 μm HPLC Column

SB.52

BIOshell^™ IgG 1000Å C4 is a high-speed, high-performance liquid chromatography column based on a new wide-pore (1000Å) Fused-Core^® particle design. The Fused-Core particle provides a thin porous shell of high-purity silica surrounding a solid silica core. This particle design exhibits very high column efficiency due to the shallow diffusion paths in the 0.5-micron thin porous shell and the small overall particle size of 2.7-microns. The densely bonded, extensively endcapped dimethylbutyl stationary phase of BIOshell IgG 1000Å C4 provides a stable, reversed-phase packing that can be used for separating high molecular weight compounds such as proteins.

UHPLC Analysis of Trastuzumab on BIOshell^™ IgG 1000 Å C4, 2.7 μm
UHPLC Analysis of IgG2 on BIOshell^™ IgG 1000 Å C4, C18, and Diphenyl, 2.7 μm

BIOshell is a trademark of sigma-aldrich Co. LLC
Fused-Core is a registered trademark of Advanced Materials Technology, Inc.

500

stainless steel hardware

suitable for USP L26

Shell thickness (0.5 μm)
Solid core (1.7 μm)

BIOshell^™

endcapped

IgG

BIOshell^™

1 ea of

0.6% carbon loading

1000 bar pressure (14500 psi)
90 ℃ max. temp.

HPLC: suitable
LC/MS: suitable
UHPLC-MS: suitable
UHPLC: suitable

5 cm × 2.1 mm

spherical silica particle platform
superficially porous particle

C4 (butyl) phase

2.7 μm

1000 Å

22 m²/g

2 - 9

reversed phase

11 - Combustible Solids

nwg