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Anti-Sodium Channel NaV1.8 antibody produced in rabbit

产品编号:4096446
规格:affinity isolated antibody, lyophilized powder
包装规格:50 μL,200 μL
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
409644650 μL3700
4096446200 μL4690
产品别名

Anti-Sodium Channel NaV1.8 antibody produced in rabbit

Anti-SCN10A

Anti-PN3

基本信息
MDL number
MFCD08705520
NACRES
NA.41
General description【一般描述】
Sodium voltage-gated channel α subunit 10 (SCN10A) codes for Nav1.8 sodium channels. It is expressed in nociceptive neurons. This gene is mapped to human chromosome 3p22.2.
Immunogen【免疫原】
peptide (C)EDEVAAKEGNSPGPQ corresponding to residues 1943-1957 of rat Nav1.8. This sequence has 14/15 residues identical in mouse and 7/15 residues identical in human.
Application【应用】
Anti-Sodium Channel NaV1.8 antibody has been used in immunohistochemistry and immunocytochemistry.
Biochem/physiol Actions【生化/生理作用】
Sodium voltage-gated channel α subunit 10 (SCN10A) plays a major role in human pain. It is involved in the pathophysiology of cerebellar deficits in MS (multiple sclerosis).
Physical form【外形】
Lyophilized from phosphate buffered saline, pH 7.4, with 1% bovine serum albumin, and 0.05 % sodium azide.
产品性质
biological source【生物来源】
rabbit
Quality Level【质量水平】
200
conjugate【偶联物】
unconjugated
antibody form【抗体形式】
affinity isolated antibody
antibody product type
primary antibodies
clone【克隆】
polyclonal
form【形式】
lyophilized powder
species reactivity
rat
technique(s)
immunohistochemistry (frozen sections): suitable using adult rat DRG
western blot: 1:200 using rat DRG lysates
UniProt accession no.【UniProt登记号】
Q62968
shipped in【运输】
wet ice
storage temp.【储存温度】
−20℃
Gene Information
human ... SCN10A(6336)
mouse ... Scn10a(20264)
rat ... Scn10a(29571)
产品说明
Target description【目标描述】
Anti-Sodium Channel NaV1.8 specifically recognizes NaV1.8. Voltage-gated sodium channels (VGSCs) are present in most excitable cells. They play a crucial role in regulating the cell excitability, being primarily responsible for the
Disclaimer【免责声明】
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
安全信息
Storage Class Code【储存分类代码】
13 - Non Combustible Solids
WGK
nwg
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