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Anti-Caspase 3 Antibody, large subunit &proform, clone 4-1-18

产品编号:4096365
规格:clone 4-1-18, Chemicon®, from mouse
包装规格:100 μG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
4096365100 μG5850
产品别名

Anti-Caspase 3 Antibody, large subunit &proform, clone 4-1-18

CPP32

基本信息
eCl@ss
32160702
NACRES
NA.41
Specificity【特异性】
Recognizes the full length 32 kDa caspase-3 protein. Highly specific to caspase-3 and shows no cross-reaction with other caspase family members. Caspase-3 is ubiquitously expressed and like other caspases is synthesized as an inactive proenzyme. Upon activation, caspase-3 is cleaved generating two smaller subunits of 17 kDa and 12 kDa. Caspase-3 is one of the most extensively studied enzyme in apoptosis. Activation of caspase-3 occurs in response to a variety of apoptotic inducers.
Immunogen【免疫原】
Recombinant full-length human caspase-3 protein
Epitope: large subunit & proform
Application【应用】
Western blot: 1:1000. The antibody will detect a band at 32 kDa corresponding to the inactive unprocessed form of caspase 3 as well as a 17-22 kDa band corresponding to the large subunit of active caspase 3.

Immunohistochemistry (frozen and paraffin): 1:500.



Optimal working dilutions must be determined by end user.
Research Sub Category
Caspases

Enzymes & Biochemistry
Research Category
Apoptosis & Cancer

Metabolism
Anti-Caspase 3 Antibody, large subunit & proform, clone 4-1-18 detects level of Caspase 3 & has been published & validated for use in WB, IH(P).
Linkage【联系】
Replaces: 04-439
Physical form【外形】
Purified immunoglobulin by protein A. Liquid in PBS, pH 7.6, with 0.1% sodium azide.
Format: Purified
Analysis Note【分析说明】
Control
POSITIVE CONTROL: 293 (human embryonic kidney) cell lysates
Other Notes【其他说明】
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Legal Information【法律信息】
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
产品性质
Quality Level【质量水平】
100
biological source【生物来源】
mouse
antibody form【抗体形式】
purified immunoglobulin
antibody product type
primary antibodies
clone【克隆】
4-1-18, monoclonal
species reactivity
human
manufacturer/tradename
Chemicon®
technique(s)
immunohistochemistry: suitable (paraffin)
western blot: suitable
isotype【同位素/亚型】
IgG2aκ
NCBI accession no.【NCBI登记号】
NM_004346.3
NM_032991.2
UniProt accession no.【UniProt登记号】
P42574
shipped in【运输】
wet ice
Gene Information
human ... CASP3(836)
产品说明
Storage and Stability【储存及稳定性】
Maintain refrigerated at 2-8°C in undiluted aliquots for up to 12 months.
Disclaimer【免责声明】
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
安全信息
Storage Class Code【储存分类代码】
10 - Combustible liquids
WGK
WGK 2
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