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Anti-ZFP36L1 Antibody

产品编号:4096280
规格:from rabbit, purified by affinity chromatography
包装规格:100 μG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
4096280100 μG6020
产品别名

Anti-ZFP36L1 Antibody

Zinc finger protein 36, C3H1 type-like 1, Butyrate response factor 1, EGF-response factor 1, ERF-1, Protein TIS11B

基本信息
eCl@ss
32160702
NACRES
NA.41
General description【一般描述】
As a member of the ZFP36/tristetraprolin (TTP) family of zinc finger proteins, ZFP36L1 serves as an RNA-binding protein (RBP) that is known to interact with AU-rich elements in the 3’-untranslated region of mRNAs, resulting in their degradation. It serves as a target for Keratinocyte-derived growth factors and cytokines. ZFP36L1 is reported to play an important role in various physiological processes, including wound healing, epidermal homeostasis, inflammation, erythroid differentiation, thymocyte development, and in the prevention of malignant transformation. Defects in the ZFPP36L1 gene have been implicated in Mutiple Sclerosis and cancer.
Specificity【特异性】
This antibody recognizes the C-terminus of ZFP36L1.
Immunogen【免疫原】
Epitope: C-terminus
KLH-conjugated linear peptide corresponding to the C-terminus of Human ZFP36L1.
Application【应用】
Research Category
Neuroscience
Anti-ZFP36L1 detects levels of ZFP36L1 proteins & has been published & validated for use in WB.
Research Sub Category
Neurodegenerative Diseases
Quality【质量】
Evaluated by Western Blot in HeLa cell lysate.

Western Blot Analysis: 1 µg/mL of this antibody detected ZFP36L1 in 10 µg of HeLa cell lysate.
Physical form【外形】
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Affinity purified
Analysis Note【分析说明】
Control
HeLa cell lysate
Other Notes【其他说明】
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
产品性质
biological source【生物来源】
rabbit
Quality Level【质量水平】
100
antibody form【抗体形式】
affinity isolated antibody
antibody product type
primary antibodies
clone【克隆】
polyclonal
purified by【纯化方式】
affinity chromatography
species reactivity
human
species reactivity (predicted by homology)
mouse (based on 100% sequence homology), canine (based on 100% sequence homology), rat (based on 100% sequence homology), horse (based on 100% sequence homology), bovine (based on 100% sequence homology)
technique(s)
western blot: suitable
NCBI accession no.【NCBI登记号】
NP_001231627
UniProt accession no.【UniProt登记号】
Q07352
shipped in【运输】
wet ice
Gene Information
human ... ZFP36L1(677)
产品说明
Target description【目标描述】
~38 kDa observed
Storage and Stability【储存及稳定性】
Stable for 1 year at 2-8°C from date of receipt.
Disclaimer【免责声明】
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
安全信息
Storage Class Code【储存分类代码】
12 - Non Combustible Liquids
WGK
WGK 1
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