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Anti-Rab11 antibody produced in rabbit
| 产品编号： | 4096159 |
| 规格： | 1 mg/mL, affinity isolated antibody, buffered aqueous solution |
| 包装规格： | 200 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
基本信息
| MDL number | MFCD01322583 |
| General description【一般描述】 | Rab11 (Ras-related protein) has three subtypes -Rab11a, Rab11b, and Rab25. Rab11a (Ras-related protein Rab-11A) belongs to the ras-like small GTP-binding protein superfamily. It is found in nonpolarized cells like fibroblasts and erythroleukemia cells. It is located on human chromosome 15q21.3-q22.31 and on mouse chromosome 9. Rab11a is expressed abundantly. |
| Immunogen【免疫原】 | synthetic peptide corresponding to amino acid residues 1-17 from human Rab11. This sequence is completely conserved in human, mouse, and rat and 94% conserved in C. elegans and amphibians. |
| Application【应用】 | Anti-Rab11 has been used in western blotting and immunohistochemistry. |
| Biochem/physiol Actions【生化/生理作用】 | Rab11a (Ras-related protein Rab-11A) participates in the modulation of basolateral to apical transcytosis. It controls TRPV5/6 (Ca2+-selective members) channel trafficking. It is essential for the production of bile canalicular in WIF-B9 cells (rat hepatoma/human fibroblast hybrid cells). |
| Physical form【外形】 | Solution in phosphate buffered saline containing 1 mg/mL bovine serum albumin and 0.05% sodium azide. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 200 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| species reactivity | rat, mouse, human |
| concentration【浓度】 | 1 mg/mL |
| technique(s) | western blot: 6.6 μg/mL using HeLa cell extract |
| UniProt accession no.【UniProt登记号】 | P62491 |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... RAB11A(8766) mouse ... Rab11a(53869) rat ... Rab11a(81830) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | nwg |
