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RSK1,有源,带 GST 标签 人

RSK1, active, GST tagged human
产品编号:4096157
规格:PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution
包装规格:10 μG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
409615710 μG6480
产品别名

RSK1,有源,带 GST 标签 人

RSK1, active, GST tagged human

MAPKAPK1A

S6K-alpha 1

RPS6KA1

HU-1

基本信息
NACRES
NA.32
General description【一般描述】
Ribosomal protein S6 kinase α-1 (RPS6KA1) or RSK1 is a member of the RSK (ribosomal S6 kinase) family that consists of growth factor-regulated serine/threonine kinases. RSK1 contains 2 nonidentical kinase catalytic domains. RSK1 encodes a predicted 735-amino acid protein containing 2 distinct consensus ATP-binding site sequences. RSK1 transcript is present in lymphocytes, skeletal muscle, liver, and adipose tissue.
Biochem/physiol Actions【生化/生理作用】
Ribosomal S6 kinases (RSKs) are implicated in the activation of the mitogen-activated kinase (MAPK) cascade and the stimulation of cell proliferation and differentiation. The protein suppresses the pro-apoptotic function of BAD by phosphorylating it. RSK1 phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signaling pathway.
Physical form【外形】
Supplied in 50 mM Tris-HCl, pH 7.5, with 150 mM NaCl, 0.2 5mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, and 25% glycerol.
Legal Information【法律信息】
PRECISIO is a registered trademark of sigma-aldrich Co. LLC
产品性质
Quality Level【质量水平】
200
recombinant【重组】
expressed in baculovirus infected Sf9 cells
product line【产品线】
PRECISIO® Kinase
Assay【测定】
≥70% (SDS-PAGE)
form【形式】
buffered aqueous glycerol solution
Specific Activity
159-215 nmol/min·mg
mol wt【分子量】
~108 kDa
UniProt accession no.【UniProt登记号】
Q15418
shipped in【运输】
dry ice
storage temp.【储存温度】
−70℃
Gene Information
human ... RPS6KA1(6195)
安全信息
Storage Class Code【储存分类代码】
10 - Combustible liquids
WGK
WGK 1
Personal Protective Equipment【个人防护装备】
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
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