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Anti-Syndecan-1 Antibody

产品编号:4096115
规格:serum, from rabbit
包装规格:100 μL
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
4096115100 μL6190
产品别名

Anti-Syndecan-1 Antibody

CD138 antigen, heparan sulfate proteoglycan fibroblast growth factor

receptor, syndecan 1, syndecan proteoglycan 1

基本信息
eCl@ss
32160702
NACRES
NA.41
General description【一般描述】
Syndecan-1, also known as CD138, is a transmembrane (Type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization. Bearing properties of both heparan sulfate and chondroitin sulfate, Syndecan-1 functions as a cell surface proteoglycan membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types.
Specificity【特异性】
Reactivity with other species has not been tested.
Predicted to cross react with human, based on 100% sequence homology.
Cat. No. AB8230 recognizes mouse Syndecan-1.
Immunogen【免疫原】
His-tagged, full-length human recombinant Syndecan-1 protein.
Application【应用】
Research Category
Cell Structure
Anti-Syndecan-1 Antibody is an antibody against Syndecan-1 for use in WB.
Research Sub Category
ECM Proteins
Quality【质量】
Evaluated on a representative lot by Western blot on mouse liver lysate using 1:1000 dilution of Anti-Syndecan-1.
Physical form【外形】
Rabbit serum containing 0.05% NaN3.
Analysis Note【分析说明】
Control
Mouse liver lysate
产品性质
biological source【生物来源】
rabbit
Quality Level【质量水平】
100
antibody form【抗体形式】
serum
antibody product type
primary antibodies
clone【克隆】
polyclonal
species reactivity
human, mouse
technique(s)
western blot: suitable
NCBI accession no.【NCBI登记号】
NM_001006946.1
UniProt accession no.【UniProt登记号】
P18827
shipped in【运输】
wet ice
产品说明
Target description【目标描述】
The expected molecular weight of monomeric Syndecan-1 is ~32 kDa; however, the core protein often migrates as an SDS-stable dimer with an approximate M.W. of 77 kDa Additionally, a high M.W. form of the protein may often be seen between 500-1000 kDa, likely the mature form of Syndecan-1, with all of its heparan and chondroitin sulfate additions. In whole tissues, this mature form often binds tightly to ECM molecules and may require solublization by urea extraction for additional SDS-PAGE analysis (Wilsie, 2006). Triton X-100 or similar mild detergents are sufficient to release the immature precursor forms of Syndecan-1.
Storage and Stability【储存及稳定性】
Maintain at -20°C for up to 1 year from date of receipt.
Disclaimer【免责声明】
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
安全信息
Storage Class Code【储存分类代码】
10 - Combustible liquids
WGK
WGK 1
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