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Src human
产品编号: | 4096112 |
规格: | ≥80% (SDS-PAGE), recombinant, expressed in baculovirus infected insect cells, buffered aqueous glycerol solution, histidine-tagged |
包装规格: | 10 μG |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
基本信息
MDL number | MFCD03458574 |
NACRES | NA.32 |
General description【一般描述】 | SRC proto-oncogene, non-receptor tyrosine kinase (SRC) belongs to the family of non-receptor tyrosine kinases. It contains an amino-terminal domain, conserved Src-homology domains (SH2 and SH3), a tyrosine kinase domain and the carboxyl-terminus. The gene encoding this protein is localized on human chromosome 20q11.23. |
Application【应用】 | Human Src has been used to study the kinetics of Src entrapped in a series of different sol-gel derived materials. |
Biochem/physiol Actions【生化/生理作用】 | SRC proto-oncogene, non-receptor tyrosine kinase (SRC) phosphorylates membrane proteins and nucleoproteins and activates various intracellular signaling cascades. It has been associated with a number of human malignancies and cancers. |
Unit Definition【单位定义】 | One unit will phosphorylate one nmole of poly(Gly:Tyr) 4:1 per minute at pH 7.5 at 30℃. |
Physical form【外形】 | Solution in 50 mM Tris pH 7.5, 0.05 mM EDTA, 1 mM DTT, 100 mM NaCl, 0.05% NP-40, and 50% glycerol. |
产品性质
Quality Level【质量水平】 | 200 |
recombinant【重组】 | expressed in baculovirus infected insect cells |
Assay【测定】 | ≥80% (SDS-PAGE) |
form【形式】 | buffered aqueous glycerol solution |
mol wt【分子量】 | 60 kDa |
concentration【浓度】 | ~0.58 mg/mL protein (Bradford assay) |
UniProt accession no.【UniProt登记号】 | P12931 |
application(s) | cell analysis |
shipped in【运输】 | dry ice |
storage temp.【储存温度】 | −70℃ |
Gene Information | human ... SRC(6714) |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | WGK 1 |