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Milli-Mark® Anti-CD64-PE Antibody, clone 10.1
产品别名
Milli-Mark® Anti-CD64-PE Antibody, clone 10.1
High affinity immunoglobulin gamma Fc receptor I, IgG Fc receptor I, Fc-gamma RIA, FcgammaRIa, Fc-gamma RI, FcRI
基本信息
eCl@ss | 32160702 |
NACRES | NA.44 |
General description【一般描述】 | CD64 is the high-affinity IgG Fc receptor belonging to the immunoglobulin supergene family (Guyre, 2002). CD64 is a 72 kDa glycoprotein which binds monomeric IgG (human IgG>>IgG>>>IgG4>>>IgG2 and mouse IgG3>IgG2a>>>IgG1, IgG2b). Three genes: FcγR1A, FcγR1B and FcγR1C, which have >98 percent identity at the nucleotide level, have been identified and mapped to chromosome 1, band q21.1 (Sun,1997)). The FcγR1A gene, which specified the high-affinity IgG receptor, encodes three C2-type Ig-like extracellular domains, a 21 amino acid transmembrane region, and a charge cytoplasmic tail of 61 amino acids (Sun, 1997)(van de Winkel,1993). |
Specificity【特异性】 | Antibody recognizes Human CD64 antigen. |
Immunogen【免疫原】 | Human rheumatoid synovial fluid cells and monocytes. |
Application【应用】 | Milli-Mark Anti-CD64-PE Antibody, clone 10.1 detects level of CD64 & has been published & validated for use in FC. Research Sub Category Immunoglobulins & Immunology Research Category Inflammation & Immunology |
Quality【质量】 | Evaluated by flow cytometry using human PBMCs |
Physical form【外形】 | Protein A purified Purified Mouse monoclonal IgG1 conjugated to PE in 0.05M Tris-HCl buffer with 1% BSA, Sodium Azide at 0.097% at pH 7.2. |
Analysis Note【分析说明】 | Control PBMC′s |
Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
Legal Information【法律信息】 | MILLI-MARK is a registered trademark of Merck KGaA, Darmstadt, Germany |
产品性质
Quality Level【质量水平】 | 100 |
biological source【生物来源】 | mouse |
conjugate【偶联物】 | PE |
antibody form【抗体形式】 | purified immunoglobulin |
antibody product type | primary antibodies |
clone【克隆】 | 10.1, monoclonal |
species reactivity | human |
manufacturer/tradename | Milli-Mark® |
technique(s) | flow cytometry: suitable |
isotype【同位素/亚型】 | IgG1κ |
NCBI accession no.【NCBI登记号】 | NP_000034.1 |
UniProt accession no.【UniProt登记号】 | P12314 |
shipped in【运输】 | wet ice |
产品说明
Target description【目标描述】 | 72 kDa (Sun W, 1997) |
Storage and Stability【储存及稳定性】 | Maintained refrigerated at 2-8°C from date of receipt. Protected from light in undiluted aliquots for 6 months from date of receipt. |
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | WGK 2 |