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Anti-Serotonin Transporter Antibody
产品别名
Anti-Serotonin Transporter Antibody
solute carrier family 6 (neurotransmitter transporter, serotonin), member 4, sodium-dependent serotonin transporter, serotonin transporter, Solute carrier family 6 member 4, Na+/Cl- dependent serotonin transporter, 5HT transporter, 5-hydroxytryptamine tr
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
General description【一般描述】 | This gene encodes an integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. The encoded protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein is a target of psychomotor stimulants, such as amphetamines and cocaine, and is a member of the sodium:neurotransmitter symporter family. A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake and may play a role in sudden infant death syndrome, aggressive behavior in Alzheimer disease patients, and depression-susceptibility in people experiencing emotional trauma. |
Specificity【特异性】 | Other species have not been tested. The antibody reacts with the 70 kDa serotonin transporter protein. |
Immunogen【免疫原】 | Epitope: Center region This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the center region of human serotonin transporter. |
Application【应用】 | This Anti-Serotonin Transporter Antibody is validated for use in WB for the detection of Serotonin Transporter. Research Category Neuroscience Research Sub Category Ion Channels & Transporters |
Quality【质量】 | Western Blot Analysis: 1:1000 dilution of this antibody detected serotonin transporter on human lung lysate. |
Linkage【联系】 | Replaces: AB1594P |
Physical form【外形】 | Purified in 0.1M Tris-Glycine (pH7.4) 150mM NaCl with 0.05% NaN3. Antigen Affinity Purified |
Analysis Note【分析说明】 | Control Western Blot : Human lung lysate. |
产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 100 |
antibody form【抗体形式】 | affinity isolated antibody |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
purified by【纯化方式】 | affinity chromatography |
species reactivity (predicted by homology) | human (100% homology), rat (100% homology), bovine (100% homology), chimpanzee (100% homology), horse (100% homology), mouse (100% homology), monkey (100% homology), sheep (100% homology) |
concentration【浓度】 | 1 mg/mL |
technique(s) | western blot: suitable |
UniProt accession no.【UniProt登记号】 | P31645 |
shipped in【运输】 | wet ice |
Gene Information | human ... HTT(3064) |
产品说明
Target description【目标描述】 | 70 kDa |
Storage and Stability【储存及稳定性】 | Store at 2-8°C for 1 year from date of receipt. |
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | WGK 1 |