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Anti-Cocaine and Amphetamine Related Transcript Antibody
产品别名
Anti-Cocaine and Amphetamine Related Transcript Antibody
CART/CARP
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
Specificity【特异性】 | Recognizes Cocaine and Amphetamine Related Transcript (CART). CART has been found to control satiety modulating the actions of two key regulators of food intake, leptin and NPY. Starvation decreases CART levels in the arcuate nucleus (Kristensen et al. 1998). Obese animals have virtually no CART. CART inhibits both normal and starvation-induced feeding, and completely inhibits NPY-induced feeding. Immunoneutralization of CART by administration of anti-CART resulted into higher food intake suggesting that CART is an endogenous regulator of food intake. |
Immunogen【免疫原】 | Mouse/rat CART peptide (55-102). |
Application【应用】 | Research Category Neuroscience Detect Cocaine & Amphetamine Related Transcript using this Anti-Cocaine & Amphetamine Related Transcript Antibody validated for use in ELISA, WB, IH. Western blotting: 1-10 μg/mL using ECL. Immunohistochemistry: It has been reported that the antibody will recognize CART in neurons (cell bodies) from the rat hypothalamic arcuate nucleus. ELISA: 1:10,000-1:50,000 using 50-100 ng control peptide per well. Optimal working dilutions must be determined by the end user. Research Sub Category CNS Control of Metabolism Reward & Addiction |
Physical form【外形】 | Affinity purified immunoglobulin. Liquid in PBS with 0.1% BSA |
Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
Legal Information【法律信息】 | CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany |
产品性质
biological source【生物来源】 | chicken |
Quality Level【质量水平】 | 100 |
antibody form【抗体形式】 | affinity purified immunoglobulin |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
purified by【纯化方式】 | affinity chromatography |
species reactivity | mouse, rat |
manufacturer/tradename | Chemicon® |
technique(s) | ELISA: suitable immunohistochemistry: suitable western blot: suitable |
isotype【同位素/亚型】 | IgY |
NCBI accession no.【NCBI登记号】 | NM_004291.2 |
UniProt accession no.【UniProt登记号】 | Q16568 |
shipped in【运输】 | dry ice |
产品说明
Storage and Stability【储存及稳定性】 | Maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles. |
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | WGK 2 |