Anti-Phosphatidylserine Receptor antibody produced in rabbit

MFCD04040521

Phosphatidylserine Receptor (PSR) is an evolutionarily conserved glycoprotein that is widely expressed in cells and tissues. It is very susceptible to cleavage by protease or elastase. PSR engagement plays an important role in macro-pinocytosis and uptake of tethered apoptotic cells. Cooperation with other receptors and their ligands may also be needed for ingestion of apoptotic cells. PSR is involved in suppression of inflammatory and immune responses.
Phosphatidylserine receptor belongs to the group of Jumonji domain containing protein 6 (JMJD6). It is known to be localized to the phagocytes. PSR is an evolutionarily conserved glycoprotein that is widely expressed in cells and tissues.

Anti-Phosphatidylserine Receptor (PSR) recognizes human and mouse phosphatidylserine receptor (PSR). Detection of the phosphatidylserine receptor by immunoblotting is specifically inhibited by the immunizing peptide, a synthetic peptide corresponding to amino acid residues 363-381 of the human phosphatidylserine receptor, conjugated to maleimide-activated KLH as immunogen.

synthetic peptide corresponding to amino acid residues 363-381 of the human phosphatidylserine receptor conjugated to maleimide-activated KLH. The corresponding sequence in mouse differs by one amino acid.

Anti-Phosphatidylserine Receptor antibody is sutiable for use in immunoprecipitation and immunoblotting (~50-70 kDa) applications.

Phosphatidylserine receptor (PSR) is very susceptible to cleavage by protease or elastase. PSR engagement plays an important role in macro-pinocytosis and uptake of tethered apoptotic cells. Cooperation with other receptors and their ligands may also be needed for ingestion of apoptotic cells. PSR is involved in suppression of inflammatory and immune responses.

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin and 15 mm sodium azide.

rabbit

200

unconjugated

affinity isolated antibody

primary antibodies

polyclonal

buffered aqueous solution

antigen 50-70 kDa

mouse, human

1-1.5 mg/mL

immunoprecipitation (IP): suitable
microarray: suitable
western blot: 1:1,000 using whole extracts of human HeLa or A549 cells
western blot: 1:500 using whole extracts of mouse NIH3T3 cells

Q6NYC1

dry ice

−20℃

human ... JMJD6(23210)
mouse ... Jmjd6(107817)

200 μL in glass bottle

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12 - Non Combustible Liquids

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