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16:0-5 Doxyl PC
产品编号: | 4095627 |
规格: | 1-palmitoyl-2-stearoyl-(5-doxyl)-sn-glycero-3-phosphocholine, powder |
CAS NO: | 188004-24-2 |
包装规格: | 1 MG |
产品类别: | 进口试剂 |
品牌: | Avanti |
优惠价: | 立即咨询 |
产品价格查看更多规格...
产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
4095627 | 1 MG | 7080 |
产品别名
188004-24-2
16:0-5 Doxyl PC
基本信息
Empirical Formula【经验(实验)分子式】 | C46H90N2O10P |
Molecular weight | 862.19 |
NACRES | NA.25 |
General description【一般描述】 | Phosphatidylcholine (PC), a strong bilayer-forming lipid is the most common phospholipid in mammalian membranes. The excretory and secretory products of helminths has a small hapten-like portion called phosphorylcholine (PC). The 5th carbon of the sn-2 stearic acid chain of 1-palmitoyl-2-stearoyl-(5-doxyl)-sn-glycero-3-phosphocholine analog has a Doxyl PC, a spin probe attached to it covalently. Avanti′s nitroxide spin product listing is a group of compounds designed to act as membrane probes. A variety of positions down the hydrophobic chain are labeled with the nitroxide functional groups to allow probing the membrane at various depths. These compounds have been synthesized from 1-palmitoyl-2-hydroxy-sn-glycerol-3-phosphocholine with the product being purified by column chromatography. Various n-doxyl phosphocholines have been recently used as biophysical tools to elucidate membrane trafficking with phosphatidylinositol transfer proteins and as fluorescent quenchers in lipid bilayer structural studies. |
Application【应用】 | 16:0-5 Doxyl PC may be used:
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Biochem/physiol Actions【生化/生理作用】 | Phosphatidylcholine (PC) lowers the levels of cholesterol and triglycerides. |
Preparation Note【制备说明】 | Product use: To prevent aggregation, prepare water-based solutions of 2 mM stock solutions of n-DOXYL PCs and store in plastic. Dilute stock solutions to 0.03- 0.1 mM solutions for EPR studies. For liposome preparations in fluorescent quenching measurements, dissolve the doxyl lipid in 150 μl absolute ethanol for a concentration of 40.3 mM , Additional supplemental information. |
产品性质
Assay【测定】 | >99% (TLC) |
form【形式】 | powder |
manufacturer/tradename | Avanti Polar Lipids 810601P |
shipped in【运输】 | dry ice |
storage temp.【储存温度】 | −20℃ |
packaging【包装】 | 5 mL Clear Glass Sealed Ampule (810601P-1mg) |
安全信息
Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |