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Monoclonal Anti-Interleukin-4-R-Phycoerythrin antibody produced in mouse
产品编号: | 4095546 |
规格: | clone 3007.11, purified immunoglobulin, buffered aqueous solution |
包装规格: | 100 TEST |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品别名
Monoclonal Anti-Interleukin-4-R-Phycoerythrin antibody produced in mouse
Monoclonal Anti-Interleukin-4
Anti-IL-4
基本信息
NACRES | NA.41 |
Specificity【特异性】 | The conjugates will identify and quantitate cells containing intracellular forms of human IL-4. |
Immunogen【免疫原】 | recombinant human IL-4 |
Biochem/physiol Actions【生化/生理作用】 | Interleukin-4 (IL-4) is a T cell derived chemokine that stimulates the Th2 mediated immune response and proliferation of B cells. The effects of IL-4 are mediated by two types of receptors, type I receptor consisting of IL-4Rα and common γ chain and type II receptor composed of IL-4Rα and IL-13Rα1. The signaling stimulated by IL-4 leads to activation of JAK/STAT6 and IRS-mediated PI3K/Akt pathway. IL-4 is responsible for endocytic activity of macrophages, chemotaxis of leukocytes in response to inflammation, angiogenesis and regulation of nitric oxide metabolism in macrophages. Conjugation of R-Phycoerythrin to the antibody enables its use in immunofluorescent techniques. |
Physical form【外形】 | 25 μg of antibody in 1.0 mL of saline containing up to 0.5% bovine serum albumin. Contains 0.1% sodium azide as a preservative. |
Preparation Note【制备说明】 | Purified antibody is conjugated to R-phycoerythrin (PE). |
产品性质
Quality Level【质量水平】 | 200 |
biological source【生物来源】 | mouse |
conjugate【偶联物】 | phycoerythrin (R-PE) conjugate |
antibody form【抗体形式】 | purified immunoglobulin |
antibody product type | primary antibodies |
clone【克隆】 | 3007.11, monoclonal |
form【形式】 | buffered aqueous solution |
species reactivity | human |
technique(s) | flow cytometry: suitable |
isotype【同位素/亚型】 | IgG1 |
UniProt accession no.【UniProt登记号】 | P05112 |
shipped in【运输】 | wet ice |
storage temp.【储存温度】 | 2-8℃ |
Gene Information | human ... IL4(3565) |
产品说明
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
WGK | WGK 3 |
Personal Protective Equipment【个人防护装备】 | dust mask type N95 (US), Eyeshields, Gloves |