TEMPOL-CAS 2226-96-2-Calbiochem

C₉H₁₈NO₂

172.24

MFCD00006478

A stable, cell-permeable nitroxide that acts as a free radical scavenger and nitric oxide spin trap. Induces oxidative stress and enhances the levels of p21^WAF1 in HL-60 cells in a dose-dependent manner. Reported to reduce organ injury following hemorrhagic shock. Exhibits radio-protective and anti-proliferative properties.
A stable, cell-permeable nitroxide free radical that acts as a radical scavenger and nitric oxide spin trap. Induces oxidative stress and enhances the levels of p21^WAF1 in HL-60 cells in a dose-dependent manner. Reported to reduce organ injury following hemorrhagic shock. Exhibits radio-protective and anti-proliferative properties.

Cell permeable: yes
Product does not compete with ATP.
Reversible: no
Primary Target
Free radical scavenger and nitric oxide spin trap

Toxicity: Harmful (C)

Prepare fresh solutions. Following reconstitution, aliquot and freeze (-20°C).

Gariboldi, M.B., et al. 2000. Free Radic. Biol. Med.29, 633.
Miura, Y., et al. 2000. J. Radiat. Res. (Tokyo)41, 103.
Mota-Filipe, H., et al. 1999. Shock 12, 255.

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

100

≥97% total nitrogen (N) basis

crystals
powder

Calbiochem^®

OK to freeze
protect from light

orange

DMSO: 5 mg/mL
ethanol: soluble
water: soluble

ambient

−20℃

1S/C9H18NO2/c1-8(2)5-7(11)6-9(3,4)10(8)12/h7,11H,5-6H2,1-4H3

UZFMOKQJFYMBGY-UHFFFAOYSA-N

500 mg in Plastic ampoule
Packaged under inert gas

GHS05,GHS07

Danger

H302 - H318

P264 - P270 - P280 - P301 + P312 - P305 + P351 + P338 - P501

Acute Tox. 4 Oral - Eye Dam. 1

11 - Combustible Solids

WGK 1

294.8 °F - DIN 51758

146 ℃ - DIN 51758