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Monoclonal Anti-CD3-FITC antibody produced in mouse
产品编号: | 4092506 |
规格: | clone UCHT-1, purified immunoglobulin, buffered aqueous solution |
包装规格: | 50 TEST |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品别名
Monoclonal Anti-CD3-FITC antibody produced in mouse
Monoclonal Anti-CD3
基本信息
NACRES | NA.44 |
General description【一般描述】 | CD3e molecule, ε (CD3E) is a polypeptide encoded by the CD3E gene in humans. It resides on chromosome 11. The CD3ε cytoplasmic domain of the T cell receptor binds to the inner leaflet of the plasma membrane (PM) and is accessible during early stages of T cell activation. It is specific for T lymphocytes and is found in Purkinje cells of the cerebellum as well as in gastric parietal cells of humans and other species. Cytoplasmic cyCD3 expression can only be seen during the early phase of NK-cell differentiation. |
Specificity【特异性】 | Recognizes the CD3 complex. The epitope recognized by clone no. UCHT-1 is expressed on the ε-chain of the CD3 antigen/T cell receptor complex. 3rd Workshop: code no. 126, 208 and 471 4th Workshop: paper no. T3.2 |
Immunogen【免疫原】 | human thymocytes followed by Sezary T cells. |
Application【应用】 | Monoclonal Anti-CD3-FITC antibody produced in mouse is suitable for flow cytometry (at a dilution of 10μL using 1 × 106 cells). It was also used for ADCC Assay. |
Physical form【外形】 | Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin and 15 mM sodium azide. |
Preparation Note【制备说明】 | Prepared by conjugation to fluorescein isothiocyanate isomer I (FITC). This green dye is efficiently excited at 495 nm and emits at 525 nm. |
产品性质
Quality Level【质量水平】 | 200 |
biological source【生物来源】 | mouse |
conjugate【偶联物】 | FITC conjugate |
antibody form【抗体形式】 | purified immunoglobulin |
antibody product type | primary antibodies |
clone【克隆】 | UCHT-1, monoclonal |
form【形式】 | buffered aqueous solution |
species reactivity | human |
technique(s) | flow cytometry: 10 μL using 1 × 106 cells |
isotype【同位素/亚型】 | IgG1 |
UniProt accession no.【UniProt登记号】 | P07766 |
shipped in【运输】 | wet ice |
storage temp.【储存温度】 | 2-8℃ |
Gene Information | human ... CD3E(916) |
产品说明
Target description【目标描述】 | The CD3 complex (16/20/29/22/25-28 kDa) consists of 5 polypeptide chains associated with each other and with the T cell receptor. |
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | nwg |