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Anti-Transcription Factor E3 antibody produced in chicken
产品编号: | 4090502 |
规格: | affinity isolated antibody, buffered aqueous solution |
包装规格: | 50 μG |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品别名
Anti-Transcription Factor E3 antibody produced in chicken
Anti-TFE3
Anti-Transcription factor binding to IGHM enhancer 3
基本信息
NACRES | NA.41 |
Immunogen【免疫原】 | Recombinant transcription factor binding to IGHM enhancer 3 Immunogen Sequence: GI # 8659574, sequence 432-541 |
Application【应用】 | Anti-Transcription Factor E3 antibody produced in chicken is suitable for western blotting at a working dilution of 1:500 and for cell staining at a working dilution of 1:200. |
Biochem/physiol Actions【生化/生理作用】 | TFE3 (Transcription factor E3) gene encodes a helix-loop-helix transcription factor that contains a helix-loop-helix domain and binds to MUE3-type E-box sequences (5′-CANNTG-3′). It plays a key role in transforming growth factor β (TGF-β) induced activation of the plasminogen activator inhibitor-1 (PAI-1) promoter. Chromosomal translocation resulting in the fusion of TFE3 gene to a novel gene, designated PRCC, is observed in papillary renal cell carcinomas. A chromosomal aberration in TFE3 is observed in patients with alveolar soft part sarcoma. |
Physical form【外形】 | Solution in phosphate buffered saline containing 0.02% sodium azide. |
产品性质
biological source【生物来源】 | chicken |
Quality Level【质量水平】 | 200 |
conjugate【偶联物】 | unconjugated |
antibody form【抗体形式】 | affinity isolated antibody |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
form【形式】 | buffered aqueous solution |
species reactivity | mouse, rat, human |
manufacturer/tradename | Genway 15-288-20056A |
technique(s) | western blot: suitable |
NCBI accession no.【NCBI登记号】 | NP_006512.2 |
UniProt accession no.【UniProt登记号】 | P19532 |
shipped in【运输】 | wet ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... TFE3(7030) |
产品说明
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | WGK 1 |
Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, multi-purpose combination respirator cartridge (US) |