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Anti-TACC2 Antibody
产品别名
Anti-TACC2 Antibody
transforming, acidic coiled-coil containing protein 2
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
General description【一般描述】 | TACC2, also known as transforming acidic coiled-coil-containing protein 2, belongs to the transforming acidic coiled-coil-containing (TACC) protein family. This group of proteins is defined by its highly conserved coiled-coil domain. This domain is necessary for the assignment of the centrosome-spindle apparatus during cell cycling. There are three proteins belonging to the TACC family; TACC1, TACC2, and TACC3. TACC2 has been reported as playing a necessary role in cultured cell microtubule stabilization. It has also been shown that the binding of TACC2 by T antigen can cause chromosomal instability and mitotic defects (Tei, 2009). Research into the over expression of TACC2 strongly suggests a potential function as a tumor suppressor (Tei, 2009). |
Immunogen【免疫原】 | KLH-conjugated linear peptide corresponding to the mature chain of mouse TACC2. |
Application【应用】 | Anti-TACC2 Antibody is a Rabbit Polyclonal Antibody for detection of TACC2 also known as transforming acidic coiled-coil containing protein 2 & has been validated in WB. |
Quality【质量】 | Evaluated by Western Blot in mouse testis tissue lysate. Western Blot Analysis: 2 µg/mL of this antibody detected TACC2 on 10 µg of mouse testis tissue lysate. |
Other Notes【其他说明】 | Affinity purified |
Legal Information【法律信息】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 100 |
antibody form【抗体形式】 | affinity isolated antibody |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
purified by【纯化方式】 | affinity chromatography |
species reactivity | human, mouse |
species reactivity (predicted by homology) | rat (based on 100% sequence homology) |
manufacturer/tradename | Upstate® |
technique(s) | western blot: suitable |
NCBI accession no.【NCBI登记号】 | NP_996738 |
UniProt accession no.【UniProt登记号】 | Q9JJG0 |
shipped in【运输】 | wet ice |
Gene Information | human ... TACC2(10579) |
产品说明
Target description【目标描述】 | Observed molecular weight, 73 kDa Note this protein can be highly modified and several isoforms exist. |
【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | WGK 1 |