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Anti-Histone H2A (acidic patch) Antibody
产品别名
Anti-Histone H2A (acidic patch) Antibody
H2A histone family, member Q, histone 2, H2ac, histone IIa, histone cluster 2, H2ac
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
General description【一般描述】 | Histone H2A is one of the 5 main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N terminal tail H2A is involved with the structure of the nucleosomes of the ′beads on a string′ structure. |
Specificity【特异性】 | Broad species cross-reactivity is expected. Recognizes Histone H2A, Mr 14 kDa. |
Immunogen【免疫原】 | KLH-conjugated, synthetic peptide corresponding to amino acids 88-97 (IRNDEELNKL-C) of human Histone H2A. |
Application【应用】 | Anti-Histone H2A (acidic patch) Antibody is a Rabbit Polyclonal Antibody for detection of Histone H2A (acidic patch) also known as histone 2-H2ac, histone IIa & has been validated in ChIP & WB. Research Sub Category Histones Research Category Epigenetics & Nuclear Function Immunofluorescence: Recommend Anti-phospho-Histone H2A.X (Ser139), clone JBW301, catalog #05-636. |
Quality【质量】 | Routinely evaluated by western blot on acid extracts from HeLa cell lysate. Western Blot Analysis: 1:1000-1:5000 dilutions of this lot detected Histone H2A (acidic patch) in acid extracts from HeLa cell lysate. |
Physical form【外形】 | Unpurified Rabbit antiserum polyclonal IgG in buffer containing 0.05% sodium azide. Frozen solution. |
Analysis Note【分析说明】 | Control HeLa cell extract. |
Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
Legal Information【法律信息】 | UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany |
产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 100 |
antibody form【抗体形式】 | serum |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
species reactivity | rat, human, chicken, mouse, yeast, Saccharomyces cerevisiae |
manufacturer/tradename | Upstate® |
technique(s) | ChIP: suitable western blot: suitable |
isotype【同位素/亚型】 | IgG |
NCBI accession no.【NCBI登记号】 | NP_003508 |
UniProt accession no.【UniProt登记号】 | Q16777 |
shipped in【运输】 | dry ice |
Gene Information | human ... HIST2H2AC(8338) |
产品说明
Target description【目标描述】 | 14 kDa |
Storage and Stability【储存及稳定性】 | Stable for 1 year at -20°C from date of receipt. For maximum recovery of product, centrifuge the vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. Handling Recommendations: Upon first thaw, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. |
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | WGK 1 |