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Anti-SMRTe Antibody
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
General description【一般描述】 | SMRT is 1495 amino acids and contains an 8 amino acid sequence that is not present in SMRTe (SMRT-extended), which contains 2514 amino acids. SMRTe contains an N-terminal sequence spanning over 1,000 amino acids that is not present in SMRT, but that shows significant similarity with N-CoR. SMRTe expression is regulated during cell cycle progression, suggesting a role for SMRTe in the regulation of cycle-specific gene expression in diverse signaling pathways. |
Specificity【特异性】 | SMRT isoforms |
Immunogen【免疫原】 | GST fusion-protein corresponding to residues 1146-1349 of human SMRTe |
Application【应用】 | Research Category Protein Trafficking Epigenetics & Nuclear Function Research Sub Category RNA Metabolism & Binding Proteins Histones RNA Binding Protein (RBP) Anti-SMRTe Antibody is a high quality Rabbit Polyclonal Antibody for the detection of SMRTe & has been validated in ChIP, ICC & WB. |
Quality【质量】 | routinely evaluated by immunoblot on nuclear fraction from murine brain |
Physical form【外形】 | Protein A chromatography Format: Purified 0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30% |
Analysis Note【分析说明】 | Control Mouse brain nuclear extract |
Legal Information【法律信息】 | UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany |
产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 100 |
antibody form【抗体形式】 | purified antibody |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
species reactivity | human |
manufacturer/tradename | Upstate® |
technique(s) | ChIP: suitable immunocytochemistry: suitable western blot: suitable |
isotype【同位素/亚型】 | IgG |
NCBI accession no.【NCBI登记号】 | NM_006312 |
UniProt accession no.【UniProt登记号】 | Q9Y618 |
shipped in【运输】 | wet ice |
Gene Information | human ... NCOR2(9612), TRAC(28755) |
产品说明
Target description【目标描述】 | 270kDa, 180kDa and 80kDa |
Storage and Stability【储存及稳定性】 | Store at 2–8℃ |
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | WGK 1 |