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Anti-Frizzled-7 Antibody
| 产品编号： | 4088202 |
| 规格： | from rabbit, purified by affinity chromatography |
| 包装规格： | 100 μg |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-Frizzled-7 Antibody
frizzled homolog 7, Frizzled, homolog of, 7, frizzled-7, frizzled homolog 7
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | Frizzled 7 is a multi-pass membrane protein belonging to the G-protein coupled receptor Fz/Smo family. It is a receptor for Wnt signaling, predominantly Wnt11, a crucial factor in the regulation of cellular migration and polarization during vertebrate gastrulation. Highest reported expression is in fetal kidney tissue and adult heart tissue. Lower levels have been observed in brain, placenta, adult heart, fetal lung, and squamous cell esophageal carcinomas. |
| Specificity【特异性】 | Recognizes Frizzled-7 |
| Immunogen【免疫原】 | KLH-conjugated linear peptide corresponding to human Frizzled-7. Epitope: Unknown |
| Application【应用】 | Western Blot Analysis: A previous lot detected Frizzled-7 on 10 µg of HEK293 cell lysate and rat brain microsomal fraction tissue lysate. Immunohistochemistry Analysis: 1:300 dilution from a previous lot detected Frizzled-7 in human ductal in situ and GI tract tissue. Immunocytochemistry Analysis: 1:500 dilution from a previous lot detected Frizzled-7 in A431 cells. Research Category Signaling This Anti-Frizzled-7 Antibody is validated for use in WB, IH, IC for the detection of Frizzled-7. Research Sub Category Developmental Signaling |
| Quality【质量】 | Evaluated by Western Blot in mouse brain microsomal fraction tissue lysate. Western Blot Analysis: 1 µg/mL of this antibody detected Frizzled-7 on 10 µg of mouse brain microsomal fraction tissue lysate. |
| Physical form【外形】 | Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.05% sodium azide. Affinity purified |
| Analysis Note【分析说明】 | Control Mouse brain microsomal fraction tissue lysate |
| Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| purified by【纯化方式】 | affinity chromatography |
| species reactivity | human, mouse, rat |
| technique(s) | immunocytochemistry: suitable immunohistochemistry: suitable western blot: suitable |
| NCBI accession no.【NCBI登记号】 | NP_003498.1 |
| UniProt accession no.【UniProt登记号】 | O75084 |
| shipped in【运输】 | wet ice |
产品说明
| Target description【目标描述】 | The calculated molecular weight is 64 kDa Observed at ~83 kDa, most likely due to multiple glycosolation sites. |
| Storage and Stability【储存及稳定性】 | Stable for 1 year at 2-8°C from date of receipt. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
