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Anti-SRp30a (SF2) Antibody

产品编号:4088132
规格:from rabbit
包装规格:100 μL
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
4088132100 μL5350
产品别名

Anti-SRp30a (SF2) Antibody

serine/arginine-rich splicing factor 1, pre-mRNA-splicing factor SF2, P33 subunit, SR splicing factor 1, splicing factor 2, splicing factor, arginine/serine-rich 1, Alternative-splicing factor 1

基本信息
eCl@ss
32160702
NACRES
NA.41
General description【一般描述】
SRp30a, also known as SF2, ASF-1 (alternative splicing factor 1), is a member of the highly conserved family of SR proteins, a group of serine/arginine-rich domain-containing proteins that play a critical role in regulated and constitutive splicing of precursor mRNA. The SR family of proteins is characterized as having one to two RNA recognition motifs located in the n-terminal sequence, and an RS domain within the C-terminus that is rich in serine/arginine dipeptide repeats. ASF-1 has an inhibitory role in exon skipping, in order to maintain splicing accuracy and to monitor alternative splicing. Studies have shown that ASF-1 plays a role in the regulation of caspase-9 alternative splicing as well as being a critical component for ceramide to function as a mediator of alternative splicing for the same caspase.
Immunogen【免疫原】
Linear peptide corresponding to human SRp30a.
Application【应用】
Use Anti-SRp30a (SF2) Antibody (rabbit polyclonal antibody) validated in WB, ICC to detect SRp30a (SF2) also known as serine/arginine-rich splicing factor 1, pre-mRNA-splicing factor SF2- P33 subunit, SR splicing factor 1.
Immunocytochemistry Analysis:
1:500 dilution from a representative lot detected SRp30a in NIH/3T3 cells.
Research Category
Epigenetics & Nuclear Function
Research Sub Category
RNA Metabolism & Binding Proteins
Quality【质量】
Evaluated by Western Blot in NIH/3T3 cell lysate.

Western Blot Analysis: 1:500 dilution of this antibody detected SRp30a on 10 µg of NIH/3T3 cell lysate.
Physical form【外形】
Protein A
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Format: Purified
Analysis Note【分析说明】
Control
NIH/3T3 cell lysate
产品性质
biological source【生物来源】
rabbit
Quality Level【质量水平】
100
antibody form【抗体形式】
purified antibody
antibody product type
primary antibodies
clone【克隆】
polyclonal
species reactivity
human, mouse, rat
technique(s)
immunocytochemistry: suitable
western blot: suitable
NCBI accession no.【NCBI登记号】
NP_001071634
UniProt accession no.【UniProt登记号】
Q07955
shipped in【运输】
wet ice
产品说明
Target description【目标描述】
~40 kDa observed. An uncharacterized band at ~ 50 kDa has been observed in some lysates.
Storage and Stability【储存及稳定性】
Stable for 1 year at 2-8°C from date of receipt.
Disclaimer【免责声明】
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
安全信息
Storage Class Code【储存分类代码】
12 - Non Combustible Liquids
WGK
WGK 1
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