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Anti-JAK2 Antibody

产品编号:4088109
规格:from rabbit
包装规格:100 μg
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
4088109100 μg4840
产品别名

Anti-JAK2 Antibody

Janus kinase 2, Janus kinase 2 (a protein tyrosine kinase), tyrosine-protein kinase JAK2

基本信息
eCl@ss
32160702
NACRES
NA.41
General description【一般描述】
The Janus family of tyrosine kinases (JAK) includes JAK1, JAK2, JAK3 and Tyk2. This family associates with a variety of cytokine receptors and is activated by ligand binding. Upon ligand binding to cytokine receptors, JAKs phosphorylate themselves and their associated receptors. This provides multiple binding sites for signaling proteins containing SH2 or other phospho-tyrosine-binding domains, including STATs, Shc, insulin receptor substrates and FAK.
Specificity【特异性】
This antibody recognizes the protein kinase 1 domain of JAK2.
Immunogen【免疫原】
Epitope: Protein kinase 1 domain
KLH-conjugated linear peptide corresponding to the protein kinase 1 domain of mouse JAK2.
Application【应用】
Research Sub Category
Immunological Signaling

Kinases & Phosphatases
This Anti-JAK2 Antibody is validated for use in WB, IP for the detection of JAK2.
Western Blot Analysis: 1 µg/mL from a previous lot detected JAK2 in 10 µg of L6 cell lysate.

Immunoprecipitation Analysis: 10 µg from a previous lot immunoprecipitated JAK2 from RAW264.7 cell lysate.
Research Category
Inflammation & Immunology

Signaling
Quality【质量】
Evaluated by Western Blot in RAW264.7 cell lysate.

Western Blot Analysis: 0.5 µg/mL of this antibody detected JAK2 in 10 µg of RAW264.7 cell lysate.
Physical form【外形】
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.05% sodium azide.
Format: Purified
Protein A purified
Analysis Note【分析说明】
Control
RAW264.7 cell lysate
Other Notes【其他说明】
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
产品性质
biological source【生物来源】
rabbit
Quality Level【质量水平】
100
antibody form【抗体形式】
purified antibody
antibody product type
primary antibodies
clone【克隆】
polyclonal
species reactivity
human, mouse, rat
technique(s)
immunoprecipitation (IP): suitable
western blot: suitable
NCBI accession no.【NCBI登记号】
NP_001041642
UniProt accession no.【UniProt登记号】
Q62120
shipped in【运输】
wet ice
产品说明
Target description【目标描述】
~130 kDa
Storage and Stability【储存及稳定性】
Stable for 1 year at 2-8°C from date of receipt.
Disclaimer【免责声明】
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
安全信息
Storage Class Code【储存分类代码】
12 - Non Combustible Liquids
WGK
WGK 1
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