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Anti-MYSM1/2A-DUB Antibody
产品别名
Anti-MYSM1/2A-DUB Antibody
Histone H2A deubiquitinase MYSM1, 2A-DUB, Myb-like, SWIRM and MPN domain-containing protein 1
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | Histone H2A deubiquitinase MYSM, often referred to as 2A-DUB is metalloprotease that specifically deubiquitinates monoubiquitinated histone H2A. 2A-DUB regulates transcription by coordinating histone acetylation and deubiquitination, and destabilizing the association of linker histone H1 with nucleosomes. The 2A-DUB mechanism may just be one of many H2A ubiquitination proteins that have the ability to regulate transcription. 2A-DUB is also essential for cell cycle progression and gene expression. |
| Immunogen【免疫原】 | Recombinant protein corresponding to human of MYSM1. |
| Application【应用】 | Research Category Epigenetics & Nuclear Function Anti-MYSM1/2A-DUB Antibody is a Rabbit Polyclonal Antibody for detection of MYSM1/2A-DUB also known as Histone H2A deubiquitinase MYSM1 & has been validated in WB. |
| Quality【质量】 | Evaluated by Western Blot in NIH/3T3 cell lysate. Western Blot Analysis: 1:1,000 dilution of this antibody detected MYSM1 on 10 µg of NIH/3T3 cell lysate. |
| Physical form【外形】 | Rabbit polyclonal serum containing 0.05% sodium azide. Unpurified |
| Analysis Note【分析说明】 | Control NIH/3T3 cell lysate |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| antibody form【抗体形式】 | serum |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| species reactivity | mouse, human |
| technique(s) | western blot: suitable |
| NCBI accession no.【NCBI登记号】 | NP_001078956 |
| UniProt accession no.【UniProt登记号】 | Q5VVJ2 |
| shipped in【运输】 | wet ice |
| Gene Information | human ... MYSM1(114803) |
产品说明
| Target description【目标描述】 | ~100 kDa observed. Uncharacterized bands at ~26, ~35, ~49 and ~66 kDa may be observed in in some lysates. Bands at ~66 and ~26 kDa may represent isoforms resulting from alternative splicing. |
| Storage and Stability【储存及稳定性】 | Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
| WGK | WGK 1 |
