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Anti-MYSM1/2A-DUB Antibody

产品编号:4087735
规格:serum, from rabbit
包装规格:100 μL
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
4087735100 μL5350
产品别名

Anti-MYSM1/2A-DUB Antibody

Histone H2A deubiquitinase MYSM1, 2A-DUB, Myb-like, SWIRM and MPN domain-containing protein 1

基本信息
eCl@ss
32160702
NACRES
NA.41
General description【一般描述】
Histone H2A deubiquitinase MYSM, often referred to as 2A-DUB is metalloprotease that specifically deubiquitinates monoubiquitinated histone H2A. 2A-DUB regulates transcription by coordinating histone acetylation and deubiquitination, and destabilizing the association of linker histone H1 with nucleosomes. The 2A-DUB mechanism may just be one of many H2A ubiquitination proteins that have the ability to regulate transcription. 2A-DUB is also essential for cell cycle progression and gene expression.
Immunogen【免疫原】
Recombinant protein corresponding to human of MYSM1.
Application【应用】
Research Category
Epigenetics & Nuclear Function
Anti-MYSM1/2A-DUB Antibody is a Rabbit Polyclonal Antibody for detection of MYSM1/2A-DUB also known as Histone H2A deubiquitinase MYSM1 & has been validated in WB.
Quality【质量】
Evaluated by Western Blot in NIH/3T3 cell lysate.

Western Blot Analysis: 1:1,000 dilution of this antibody detected MYSM1 on 10 µg of NIH/3T3 cell lysate.
Physical form【外形】
Rabbit polyclonal serum containing 0.05% sodium azide.
Unpurified
Analysis Note【分析说明】
Control
NIH/3T3 cell lysate
产品性质
biological source【生物来源】
rabbit
Quality Level【质量水平】
100
antibody form【抗体形式】
serum
antibody product type
primary antibodies
clone【克隆】
polyclonal
species reactivity
mouse, human
technique(s)
western blot: suitable
NCBI accession no.【NCBI登记号】
NP_001078956
UniProt accession no.【UniProt登记号】
Q5VVJ2
shipped in【运输】
wet ice
Gene Information
human ... MYSM1(114803)
产品说明
Target description【目标描述】
~100 kDa observed. Uncharacterized bands at ~26, ~35, ~49 and ~66 kDa may be observed in in some lysates. Bands at ~66 and ~26 kDa may represent isoforms resulting from alternative splicing.
Storage and Stability【储存及稳定性】
Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Disclaimer【免责声明】
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
安全信息
Storage Class Code【储存分类代码】
10 - Combustible liquids
WGK
WGK 1
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