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Anti-NOTCH4 antibody produced in rabbit

产品编号:4087642
规格:~1 mg/mL, affinity isolated antibody, buffered aqueous solution
包装规格:100 μG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
4087642100 μG4340
产品别名

Anti-NOTCH4 antibody produced in rabbit

Anti-INT3

Anti-Notch homolog 4 (Drosophila)

基本信息
NACRES
NA.41
General description【一般描述】
NOTCH homolog-4 (NOTCH4) is expressed in breast cancer.
Immunogen【免疫原】
synthetic peptide corresponding to residues 1506-1524 of human NOTCH4. This sequence is 89% identical in mouse and rat.
Biochem/physiol Actions【生化/生理作用】
NOTCH homolog-4 (NOTCH4) has an intracellular domain which detaches from the protein on activation. This domain then translocates to the nucleus and modulates transcription of genes. NOTCH4 also activates various pathways and contributes to carcinogenesis. Mutations in the gene encoding the protein may be linked to schizophrenia.
Physical form【外形】
solution in phosphate buffered saline, containing 0.02% sodium azide.
产品性质
biological source【生物来源】
rabbit
Quality Level【质量水平】
200
conjugate【偶联物】
unconjugated
antibody form【抗体形式】
affinity isolated antibody
antibody product type
primary antibodies
clone【克隆】
polyclonal
form【形式】
buffered aqueous solution
mol wt【分子量】
antigen ~230 kDa
antigen ~80 kDa
species reactivity
human, mouse, rat
concentration【浓度】
~1 mg/mL
technique(s)
immunohistochemistry: 1:100-1:200
western blot: 1:500-1:1,000
UniProt accession no.【UniProt登记号】
Q99466
application(s)
research pathology
shipped in【运输】
dry ice
storage temp.【储存温度】
−20℃
Gene Information
human ... NOTCH4(4855)
mouse ... Notch4(18132)
rat ... Notch4(406162)
产品说明
Disclaimer【免责声明】
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
安全信息
Storage Class Code【储存分类代码】
12 - Non Combustible Liquids
WGK
nwg
Personal Protective Equipment【个人防护装备】
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
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