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Anti-Nuclear factor 1/C Antibody

产品编号:4087602
规格:serum, from rabbit
包装规格:100 μL
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
4087602100 μL4840
产品别名

Anti-Nuclear factor 1/C Antibody

Nuclear factor 1 C-type, NF1-C, CCAAT-box-binding transcription factor, CCAAT-box-binding transcription factor, CTF, Nuclear factor I/C, NF-I/C, NFI-C, TGGCA-binding protein

基本信息
eCl@ss
32160702
NACRES
NA.41
General description【一般描述】
Through evolution, eukaryotic cells have incorporated numerous viral promoter elements and incorporated them as part of their own gene regulatory elements. Nuclear factor 1/C was originally recognized as a transcription factor that bound the origin of replication for adenovirus type 2. Nuclear factor 1/C belongs to the CTF/NF-I family of eukaryotic DNA replication and transcription factors and is important in regulating the expression of many cellular developmental systems such as that of tooth development as well as multiple TGF-beta1 signaling mediated pathways systems.
Specificity【特异性】
Recognizes multiple isoforms of Nuclear factor 1/C
Immunogen【免疫原】
Recombinant protein corresponding to full length Human NFIC.
Epitope: C-terminus
Application【应用】
Research Sub Category
Transcription Factors
Chromatin Immunoprecipitation Assay (ChIP): A representative lot of this antibody has been reported to work in ChIP. See Hebbar, P.B., and Archer, T.K. (2007), Vicent G.P. et al. (2010), and Brun, M., et al. (2013).

Electrophoretic Mobility Shift Assay (EMSA): A representative lot of this antibody has been reported to work in EMSA. See Johansson E.M., et al. (2003) and Kannius-Janson, M., et al. (2002).
This Anti-Nuclear factor 1/C Antibody is validated for use in Western Blotting and Chromatin Immunoprecipitation (ChIP) and Electrophoretic Mobility Shift Assay for the detection of Nuclear factor 1/C.
Research Category
Epigenetics & Nuclear Function
Quality【质量】
Evaluated by Western Blotting in U251 cell lysate.

Western Blotting Analysis: A 1:1000 dilution of this antibody detected NFIC isoforms at ~45-55 kDa in a U251 cell lysate.
Physical form【外形】
Unpurified
Rabbit polyclonal serum containing 0.05% sodium azide.
Other Notes【其他说明】
Concentration: Please refer to lot specific datasheet.
产品性质
biological source【生物来源】
rabbit
Quality Level【质量水平】
100
antibody form【抗体形式】
serum
antibody product type
primary antibodies
clone【克隆】
polyclonal
species reactivity
rat, mouse, human
technique(s)
ChIP: suitable
electrophoretic mobility shift assay: suitable
western blot: suitable
NCBI accession no.【NCBI登记号】
NP_001231931
UniProt accession no.【UniProt登记号】
P08651
shipped in【运输】
wet ice
产品说明
Target description【目标描述】
~45-55 kDa observed
Storage and Stability【储存及稳定性】
Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Disclaimer【免责声明】
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
安全信息
Storage Class Code【储存分类代码】
10 - Combustible liquids
WGK
WGK 1
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