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Anti-mGluR4 Antibody

产品编号:4087598
规格:from rabbit
包装规格:50 μG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
408759850 μG5420
产品别名

Anti-mGluR4 Antibody

glutamate metabotropic receptor 4, glutamate receptor, metabotropic 4

基本信息
eCl@ss
32160702
NACRES
NA.41
General description【一般描述】
L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities.
Specificity【特异性】
Reactivity with other species has not been determined.
Cat. # AB15097 recognizes mGluR4 (GRM4).
Immunogen【免疫原】
Recombinant Protein.
Application【应用】
This Anti-mGluR4 Antibody is validated for use in WB for the detection of mGluR4.
Research Category
Neuroscience
Research Sub Category
Neurotransmitters & Receptors
Quality【质量】
Western Blot:
Mouse Brain Lysate.
Physical form【外形】
Purified in 0.1M Tris-Glycine (pH7.4) 150mM NaCl with 0.05% NaN3.
Format: Purified
Antigen Affinity Purified
Analysis Note【分析说明】
Control
Mouse Brain Lysate.
Other Notes【其他说明】
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
产品性质
biological source【生物来源】
rabbit
Quality Level【质量水平】
100
antibody form【抗体形式】
affinity isolated antibody
antibody product type
primary antibodies
clone【克隆】
polyclonal
species reactivity
mouse, rat
technique(s)
western blot: suitable
NCBI accession no.【NCBI登记号】
NP_001013403.1
UniProt accession no.【UniProt登记号】
Q68EF4
shipped in【运输】
wet ice
产品说明
Target description【目标描述】
~101 kDa
Storage and Stability【储存及稳定性】
Stable for 1 year at 2-8ºC from date of receipt.
Disclaimer【免责声明】
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
安全信息
Storage Class Code【储存分类代码】
12 - Non Combustible Liquids
WGK
WGK 1
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