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Anti-zDHHC8 Antibody
| 产品编号： | 4087550 |
| 规格： | from rabbit, purified by affinity chromatography |
| 包装规格： | 100 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-zDHHC8 Antibody
Zinc finger DHHC domain-containing protein 8, Zinc finger protein 378, membrane-associated DHHC8 zinc finger protein, zinc finger, DHHC domain containing 8, zinc finger, DHHC domain like containing 1, zinc finger, DHHC-type containing 8
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | Six genes in the 1.5 Mb region of chromosome 22 deleted in DiGeorge/22q11 deletion syndrome–Mrpl40, Prodh, Slc25a1, Txnrd2, T10, and Zdhhc8–encode mitochondrial proteins. All six genes are expressed in the brain, and maximal expression coincides with peak forebrain synaptogenesis shortly after birth. Furthermore, their protein products are associated with brain mitochondria, including those in synaptic terminals. Among the six, only Zddhc8 influences mitochondria-regulated apoptosis when overexpressed, and appears to interact biochemically with established mitochondrial proteins. Zdhhc8 has an apparent interaction with Uqcrc1, a component of mitochondrial complex III. The two proteins are coincidently expressed in pre-synaptic processes; however, Zdhhc8 is more frequently seen in glutamatergic terminals (1). |
| Specificity【特异性】 | Cat. AB15242 recognizes the C-terminus of zDHHC8. |
| Immunogen【免疫原】 | Syntheic linear peptide. Epitope: C-Terminus |
| Application【应用】 | Anti-zDHHC8 Antibody is an antibody against zDHHC8 for use in WB. Research Category Neuroscience Research Sub Category Developmental Neuroscience |
| Quality【质量】 | Routinely evaluated by western blot in fetal human brain lysate. |
| Physical form【外形】 | ImmunoAffinity Purified Purified in PBS with 0.05% NaN3 |
| Analysis Note【分析说明】 | Control Fetal human brain |
| Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| purified by【纯化方式】 | affinity chromatography |
| species reactivity | human, rat |
| species reactivity (predicted by homology) | pig, horse, bovine, opossum, chicken, Xenopus, chimpanzee, dog, ape, mouse |
| technique(s) | western blot: suitable |
| UniProt accession no.【UniProt登记号】 | Q9ULC8 |
| shipped in【运输】 | wet ice |
产品说明
| Target description【目标描述】 | ~71 kDa |
| Storage and Stability【储存及稳定性】 | Stable for 1 year at 2-8°C from date of receipt. Handling Recommendations: Prior to removing the cap, gently centrifuge the vial and gently mix the solution. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
| WGK | WGK 2 |
