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Anti-hMOF Antibody

产品编号:4087475
规格:from rabbit
包装规格:100 μG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
4087475100 μG5680
产品别名

Anti-hMOF Antibody

Histone acetyltransferase KAT8, Lysine acetyltransferase 8, MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1, MYST-1, hMOF

基本信息
eCl@ss
32160702
NACRES
NA.41
General description【一般描述】
hMOF, also known as Histone acetyltransferase KAT8, or Lysine acetyltransferase, MOZ, YBF2/SAS3, SAS2, TIP60 protein 1, and MYST-1, and encoded by the gene KAT8/MOF/MYST1, is a histone acetyltransferase which is involved in transcriptional activation and also is a component of the MSL complex involved in acetylation of nucleosomal histone H4 producing specifically H4K16ac. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. hMOF also a component of many other MSL related complexes including the methyltransferase complexes and interacts with numerous other related proteins including BAP18, CHD8, E2F6, HSP70, INO80C, KANSL1, LAS1L, MAX, MCRS1, MGA, MOF/KAT8, PELP1, PHF20, PRP31, RING2, RUVB1/TIP49A, RUVB2/TIP49B, SENP3, TAF1, TAF4, TAF6, TAF7, TAF9 and TEX10. hMOF is localized to the nucleus and nuclear chromosomes.
Immunogen【免疫原】
Linear peptide corresponding to hMOF.
Application【应用】
Chromatin Immunoprecipitation Analysis: A representative lot from an independent laboratory immunoprecipitated hMOF from HeLa cell lysate (Wu, L., et al. (2011). Mol Cell. 43(1):132-144.).

Immunoprecipitation Analysis: A representative lot from an independent laboratory immunoprecipitated hMOF from HeLa cell lysate (Smith, E. R., et al. (2005). Mol Cell Biol. 25(21):9175-9188.).

Research Category
Epigenetics & Nuclear Function
Research Sub Category
Chromatin Biology
Anti-hMOF antibody detects level of hMOF & has been published & validated for use in hMOF.
Quality【质量】
Evaluated by Western Blotting in HUVEC cell lysate.

Western Blotting Analysis: 1 µg/mL of this antibody detected hMOF in 10 µg of HUVEC cell lysate.
Physical form【外形】
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Format: Purified
Protein G Purified
Other Notes【其他说明】
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
产品性质
biological source【生物来源】
rabbit
Quality Level【质量水平】
100
antibody form【抗体形式】
purified antibody
antibody product type
primary antibodies
clone【克隆】
polyclonal
species reactivity
human, mouse, rat
technique(s)
ChIP: suitable
western blot: suitable
NCBI accession no.【NCBI登记号】
NP_115564
UniProt accession no.【UniProt登记号】
Q9H7Z6
shipped in【运输】
wet ice
产品说明
Target description【目标描述】
~60 kDa observed. Uncharacterized band(s) may be observed in some cell lysate.
Storage and Stability【储存及稳定性】
Stable for 1 year at 2-8°C from date of receipt.
Disclaimer【免责声明】
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
安全信息
Storage Class Code【储存分类代码】
12 - Non Combustible Liquids
WGK
WGK 1
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