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Anti-RAB35 Antibody
产品编号: | 4087390 |
规格: | from rabbit, purified by affinity chromatography |
包装规格: | 100 μG |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品别名
Anti-RAB35 Antibody
Ras-related protein Rab-35, GTP-binding protein RAY, Ras-related protein Rab-1C
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
General description【一般描述】 | RAB35 is a member of the Rab GTPases identified in the human genome. It is ubiquitously expressed and regulates a fast endocytotic recycling events associated with the terminal steps of cytokinesis, the formation of immunological synapse, and peptide loading onto major histocompatibility complex III molecules. RAB35 also plays a significant role in the formation of the immunological synapse (IS) between peptide-loaded antigen presenting cells (APCs) and T cells. |
Specificity【特异性】 | This antibody recognizes RAB35 at the C-terminus. |
Immunogen【免疫原】 | KLH-conjugated linear peptide corresponding to the C-terminus of human RAB35. |
Application【应用】 | This Anti-RAB35 Antibody is validated for use in WB, IH(P) for the detection of RAB35. Immunohistochemistry Analysis: A 1:500 dilution from a representative lot detected RAB35 in normal human brain tissue. |
Quality【质量】 | Evaluated by Western Blot in human brain tissue lysate. Western Blot Analysis: 1 µg/mL of this antibody detected RAB35 on 10 µg of human brain tissue lysate. |
Other Notes【其他说明】 | Affinity purified |
产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 100 |
antibody form【抗体形式】 | affinity isolated antibody |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
purified by【纯化方式】 | affinity chromatography |
species reactivity | horse, rat, human |
species reactivity (predicted by homology) | canine (based on 100% sequence homology), equine (based on 100% sequence homology) |
technique(s) | immunohistochemistry: suitable (paraffin) western blot: suitable |
NCBI accession no.【NCBI登记号】 | NP_006852 |
UniProt accession no.【UniProt登记号】 | Q15286 |
shipped in【运输】 | wet ice |
Gene Information | human ... RAB35(11021) |
产品说明
Target description【目标描述】 | ~19 kDa observed. The calculated molecular weight is 23 kDa |
【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | WGK 1 |