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N1-Acetyl-N2-formyl-5-methoxykynuramine
产品别名
52450-38-1
N1-Acetyl-N2-formyl-5-methoxykynuramine
NSC 688263
AFMK
NSC688263
N-[3-[2-(Formylamino)-5-methoxyphenyl]-3-oxopropyl]acetamide
AFMKA
NSC-688263
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C13H16N2O4 |
| Molecular weight | 264.28 |
| MDL number | MFCD02683241 |
| General description【一般描述】 | Melatonin and its metabolites are being studied for their antioxidant properties and their protective effects against oxidative stress in both mammals and in plants. N1-Acetyl-5-methoxykynuramine (AMK) and its direct precursor N1-acetyl-N2-formyl-5-methoxykynuramine (AFMK) are two metabolites that contribute to the antioxidant properties of melatonin. |
| Application【应用】 | Metabolomics research |
| Biochem/physiol Actions【生化/生理作用】 | AFMK is a melatonin metabolite first detected in rat brain; demonstrates antioxidant and free radical scavenging activities in several experimental models; inhibits LPS-mediated production of TNFα and IL-8 in neutrophils; useful tool in the study of melatonin metabolism. |
产品性质
| Quality Level【质量水平】 | 200 |
| Assay【测定】 | ≥95% (HPLC) |
| form【形式】 | solid |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | COc1ccc(NC=O)c(c1)C(=O)CCNC(C)=O |
安全信息
| Pictograms【象形图】 | GHS06 |
| Signal word【警示用语：】 | Danger |
| Hazard Statements | H301 |
| Precautionary Statements | P264 - P270 - P301 + P310 - P405 - P501 |
| Hazard Classifications【危险分类】 | Acute Tox. 3 Oral |
| Storage Class Code【储存分类代码】 | 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects |
| WGK | WGK 3 |
