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SU086
产品别名
1017898-53-1
SU086
(2E)-3-(3-Nitrophenyl)-1-(2,4,6-trimethoxyphenyl)-2-propen-1-one
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C18H17NO6 |
| Molecular weight | 343.33 |
| MDL number | MFCD03788900 |
| Biochem/physiol Actions【生化/生理作用】 | SU086 is a cell-permeable, non-toxic, bioavailable chalcone compound that decreases HSP90 levels and impairs glycolysis. SU086 is shown to inhibit prostate cancer cell growth, migration, and invasion in vitro (10 μM) through non-androgen receptor mediated pathways. SU086 displays favorable PK profile and synergizes with enzalutamide and abiraterone to decrease prostate cancer growth in vitro and in vivo. It is a potent inhibitor of selenoprotein thioredoxin reductases (TrxRs). |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| color【颜色】 | white to beige |
| solubility【溶解性】 | DMSO: 2 mg/mL, clear (warmed) |
| storage temp.【储存温度】 | 2-8℃ |
安全信息
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
