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PSEM89S Hydrochloride salt
产品别名
1221570-55-3
PSEM89S Hydrochloride salt
(S)-2,5-Dimethoxy-N-(quinuclidin-3-yl)benzamide, Hydrochloride salt
PSEM 89S Hydrochloride salt
PSEM-89S Hydrochloride salt
N-(3S)-1-Azabicyclo[2.2.2]oct-3-yl-2,5-dimethoxybenzamide Hydrochloride salt
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C16H22N2O3 · HCl |
| Molecular weight | 326.82 |
| Biochem/physiol Actions【生化/生理作用】 | PSEM89S is a pharmacologically selective effector molecule (PSEM) that acts as a selective agonist in vitro and in vivo for chimeric pharmacologically selective actuator modules (PSAMs) composed of nAChR α7 ligand-binding domain (LBD) with L141F mutation fused to the ion pore domain (IPD) of a ligand-gated ion channel (LGIC), including glycine receptor (PSAML141F-GlyR & PSAML141F/Y115F-GlyR). 5-HT3 (PSAML141F-5-HT3 & PSAML141F/Y115F-5-HT3) and high-conductance 5-HT3 (PSAML141F-5-HT3 HC & PSAML141F/Y115F-5-HT3 HC). |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| storage condition【储存条件】 | desiccated |
| color【颜色】 | white to beige |
| solubility【溶解性】 | DMSO: 2 mg/mL, clear |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | O=C(N[C@@H]1CN2CCC1CC2)C3=C(C=CC(OC)=C3)OC.Cl |
安全信息
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
