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Amonafide
产品别名
69408-81-7
Amonafide
FA 142
NSC 308847
Nafidimide
5-Amino-2-[2-(dimethylamino)ethyl]-1H-benz[de]isoquinoline-1,3(2H)-dione
AS1413
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C16H17N3O2 |
| Molecular weight | 283.33 |
| MDL number | MFCD00866438 |
| Biochem/physiol Actions【生化/生理作用】 | Amonafide, a naphthalimides DNA intercalator, is a potent topoisomerase II inhibitor that inhibits tumor proliferation and progression. It appears that Amonafide inhibits melanoma progression through inhibition of the AKT/mTOR signaling pathway. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| color【颜色】 | white to beige |
| solubility【溶解性】 | DMSO: 2 mg/mL, clear |
| storage temp.【储存温度】 | −20℃ |
安全信息
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
