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ADA-07
产品别名
ADA-07
5-(adamantan-1-yl)-3-(hydroxyimino) indolin-2-one
结构式
基本信息
Empirical Formula【经验(实验)分子式】 | C18H20N2O2 |
Molecular weight | 296.36 |
NACRES | NA.77 |
Biochem/physiol Actions【生化/生理作用】 | ADA-07 is a potent and selective T-LAK cell-originated protein kinase (TOPK) inhibitor that binds to ATP-binding pocket. ADA-07 suppresses SUV-induced phosphorylation of ERK1/2, p38, and JNKs and subsequently inhibited AP-1 activity, and reduces SUV-induced skin carcinogenesis. |
产品性质
Assay【测定】 | ≥95% (HPLC) |
form【形式】 | powder |
color【颜色】 | yellow to brown |
solubility【溶解性】 | DMSO: 2 mg/mL, clear |
storage temp.【储存温度】 | 2-8℃ |
SMILES string | O=C(/C1=N\O)NC(C1=C2)=CC=C2C34C[C@@H](C5)C[C@@H](C[C@@H]5C4)C3 |
安全信息
Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
WGK | WGK 3 |