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Ac-SDKP trifluoroacetate
产品别名
1796568-94-9
Ac-SDKP trifluoroacetate
Ac-Ser-Asp-Lys-Pro-OH trifluoroacetate
Thymosin в4 (1-4) trifluoroacetate
Ac-SDKP-OH trifluoroacetate
Tв4 (1-4) trifluoroacetate
Goralatide trifluoroacetate
N-acetyl-L-seryl-L-a-aspartyl-L-lysyl-L-proline trifluoroacetate
AcSDKP trifluoroacetate
N-acetyl-Ser-Asp-Lys-Pro-OH trifluoroacetate
基本信息
| Empirical Formula【经验(实验)分子式】 | C20H33N5O9 · xC2HF3O2 |
| Molecular weight | 487.50 (free base basis) |
| Biochem/physiol Actions【生化/生理作用】 | Originally characterized as a "spleen colony-forming units (CFU-S) inhibitor" for its activity against hematopoietic pluripotent stem cell proliferation, Ac-SDKP (Goralatide) is an immunomodulatory and pro-angiogenic tetrapeptide derived from the N-terminal end of thymosin β4 (Tβ4 aa 1-4) via sequential enzymatic actions of meprin-α and prolyl-oligopeptidase (POP), while angiotensin converting enzyme (ACE) mediates Ac-SDKP degradation. In animal heart, kidney and brain injury studies, Ac-SDKP ameliorates end-organ damage by promoting angiogenesis, as well as by reducing inflammation and fibrosis. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥95% (HPLC) |
| form【形式】 | lyophilized powder |
| color【颜色】 | white to off-white |
| storage temp.【储存温度】 | −20℃ |
安全信息
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
