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SPA70
产品别名
931314-31-7
SPA70
1-(2,5-Dimethoxyphenyl)-4-[[4-(1,1-dimethylethyl)phenyl]sulfonyl]-5-methyl-1H-12,3-triazole
LC-1
结构式
基本信息
Empirical Formula【经验(实验)分子式】 | C21H25N3O4S |
Molecular weight | 415.51 |
MDL number | MFCD14774311 |
Biochem/physiol Actions【生化/生理作用】 | SPA70 is a cell penetrant, potent and highly selective human pregnane X receptor (hPXR) antagonist that inhibits hPXR in humanized mouse models. It inhibits hPXR-mediated drug metabolism in in primary human hepatocytes and in mouse models. |
产品性质
Assay【测定】 | ≥98% (HPLC) |
form【形式】 | powder |
color【颜色】 | white to beige |
solubility【溶解性】 | DMSO: 2 mg/mL, clear (warmed) |
storage temp.【储存温度】 | 2-8℃ |
安全信息
Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
WGK | WGK 3 |