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Pt-ttpy
产品别名
727721-37-1
Pt-ttpy
(SP-4-2)-Chloro[4′-(4-methylphenyl)-2,2′:6′,2′′-terpyridine-κN1,κN1′,κN1′′]-Platinum(1+) chloride
Tolylterpyridin-platin
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C22H17Cl2N3Pt |
| Molecular weight | 589.37 |
| Biochem/physiol Actions【生化/生理作用】 | Pt-ttpy, a metallo-organic complex, is a G-quadruplex ligand that potently induces significant telomere-associated DNA damage in cancer cells. It inhibits telomerase and/or telomere functions. Pt-ttpy induces number of chromatin defects in mitosis including chromatin bridges, ultrafine bridges (UFBs), and double-stranded breaks (DSBs). |
产品性质
| Assay【测定】 | >97% (NMR) |
| form【形式】 | powder |
| color【颜色】 | faint yellow to dark orange |
| solubility【溶解性】 | DMSO: 0.2 mg/mL (warmed) |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | CC1=CC=C(C2=CC(C3=[N+]4C=CC=C3)=[N+]5C(C6=CC=CC=[N+]6[Pt-2]54Cl)=C2)C=C1.[Cl-] |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
