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KCC-07
产品别名
315702-75-1
KCC-07
3-[[4-(2-Pyridinyl)-2-thiazolyl]amino]phenol
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C14H11N3OS |
| Molecular weight | 269.32 |
| MDL number | MFCD01121976 |
| Biochem/physiol Actions【生化/生理作用】 | KCC-07 is a brain penetrant, potent and selective inhibitor of MBD2 (methyl-CpG-binding domain protein 2) that inhibits binding of MBD2 to methylated DNA and activates brain specific angiogenesis inhibitor 1 (BAI1) inducing anti-proliferative BAI1/p53/p21 signaling. KCC-07 inhibits medulloblastoma cell proliferation, and inhibits tumor growth in mice xenograft models of medulloblastoma. |
产品性质
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| color【颜色】 | white to beige |
| solubility【溶解性】 | DMSO: 2 mg/mL, clear |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | OC1=CC(NC2=NC(C3=NC=CC=C3)=CS2)=CC=C1 |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
